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Alison Michele Schram

  1. "2019"
Formats
  1. Meeting Abstract (12)
  2. Journal Article (4)
  3. Research Letter (1)
Groups
  1. Department of Medicine (17)
  2. Early Drug Development Service (17)
  3. Gynecologic Medicine Service (17)
  4. Solid Tumor Oncology Division (17)
  5. Thoracic Oncology (12)
  6. Department of Pathology and Laboratory Medicine (11)

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People
  1. David Hyman (14)
  2. Alexander Drilon (12)
  3. Marc Ladanyi (9)
  4. Michael Berger (7)
  5. Helen Won (6)
  6. Jaclyn Hechtman (5)

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Years
  1. 2019 (17)
Publications
  1. Cancer Research (7)
  2. Annals of Oncology (2)
  3. JCO Precision Oncology (2)
  4. Journal of Clinical Oncology (2)
  5. Clinical Cancer Research (1)
  6. Journal of Thoracic Oncology (1)

More Publications

Publishers
  1. American Association for Cancer Research (9)
  2. American Society of Clinical Oncology (4)
  3. Oxford University Press (2)
  4. Elsevier Inc. (1)
  5. Nature Publishing Group (1)

Results (17)

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  • Clinical proof of concept for MCLA-128, a bispecific HER2/3 antibody therapy, in NRG1 fusion-positive cancers
    Meeting Abstract

    Schram, A. M.; O'Reilly, E. M.; Somwar, R.; Benayed, R.; Shameem, S.; Chauhan, T.; Torrisi, J.; Ford, J.; Maussang, D.; Wasserman, E.; more...
    Molecular Cancer Therapeutics (2019)

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  • Real-world outcomes of an automated physician support system for genome-driven oncology
    Journal Article

    Tao, J. J.; Eubank, M. H.; Schram, A. M.; Cangemi, N.; Pamer, E.; Rosen, E. Y.; Schultz, N.; Chakravarty, D.; Philip, J.; Hechtman, J. F.; more...
    JCO Precision Oncology (2019)

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  • Generation and characterization of novel preclinical disease models of NSCLC with NRG1 rearrangements to improve therapy
    Meeting Abstract

    Gladstone, E.; Vojnic, M.; Offin, M.; Delasos, L.; Lui, A.; Siau, E.; Sato, H.; Benayed, R.; Kurth, R.; Mattar, M.; more...
    Journal of Thoracic Oncology (2019)

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  • A phase II basket study of MCLA-128, a bispecific antibody targeting the HER3 pathway, in NRG1 fusion-positive advanced solid tumours
    Meeting Abstract

    Schram, A. M.; Drilon, A.; Macarulla Mercade, T.; O'Reilly, E. M.; Rodon, J. A.; Wolpin, B. M.; Ou, S. H. I.; Kim, D. W.; Yang, J. C. H.; Lam, Y. C. J.; more...
    Annals of Oncology (2019)

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  • Phase I dose escalation of MSC-1, a humanized anti-LIF monoclonal antibody, in patients (pts) with advanced solid tumours: Updated results
    Meeting Abstract

    Borazanci, E.; Schram, A.; Brana, I.; Vieito Villar, M.; Garralda, E.; Spreafico, A.; Oliva, M.; Lakhani, N.; Wasserman, R.; Hoffman, K.; more...
    Annals of Oncology (2019)

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  • Clinicopathologic characteristics of NRG1 fusion-positive cancers: A single-institution study
    Meeting Abstract

    Schram, A. M.; Benayed, R.; Somwar, R.; Rekhtman, N.; Arcila, M. E.; Ladanyi, M.; Hyman, D. M.; Drilon, A. E.
    Journal of Clinical Oncology (2019)

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  • NRG1 fusion-positive lung cancers: Clinicopathologic profile and treatment outcomes from a global multicenter registry
    Meeting Abstract

    Duruisseaux, M.; Liu, S. V.; Han, J. Y.; Gounant, V.; Shih, J. Y.; Schram, A. M.; Schrock, A. B.; Ali, S. M.; Magne, F.; Monnet, I.; more...
    Journal of Clinical Oncology (2019)

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  • Paired tumor and cfDNA in patients with HER2-mutant solid tumors treated with neratinib reveals convergence of multiple on-target resistance mechanisms: Results from the SUMMIT "Basket" Trial
    Meeting Abstract

    Won, H. H.; Selcuklu, S. D.; Piha-Paul, S. A.; Saura, C.; Rodon, J.; Mayer, I. A.; Loi, S.; Shapiro, G. I.; Lu, J.; Brufsky, A.; more...
    Cancer Research (2019)

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  • Hyperactivation of mTORC1 drives acquired resistance to the pan -HER tyrosine kinase inhibitor neratinib in HER2-mutant cancers
    Meeting Abstract

    Sudhan, D. R.; Guerrero-Zotano, A.; Won, H.; Ericsson, P. G.; Liu, Q.; Dugger, T.; Koch, J.; Schram, A.; Servetto, A.; Cutler, R.; more...
    Cancer Research (2019)

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  • Initial results from the phase I study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors
    Meeting Abstract

    Schram, A.; Spreafico, A.; Oliva, M.; Brana, I.; Garralda, E.; Lakhani, N.; Von Hoff, D.; Borazanci, E.; Pandya, N.; Hoffman, K.; more...
    Cancer Research (2019)

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