Hyperactivation of mTORC1 drives acquired resistance to the pan -HER tyrosine kinase inhibitor neratinib in HER2-mutant cancers Meeting Abstract


Authors: Sudhan, D. R.; Guerrero-Zotano, A.; Won, H.; Ericsson, P. G.; Liu, Q.; Dugger, T.; Koch, J.; Schram, A.; Servetto, A.; Cutler, R.; Lalani, A.; Bryce, R.; Auerbach, A.; Hanker, A.; Arteaga, C. L.
Abstract Title: Hyperactivation of mTORC1 drives acquired resistance to the pan -HER tyrosine kinase inhibitor neratinib in HER2-mutant cancers
Meeting Title: 110th Annual Meeting of the American Association for Cancer Research (AACR)
Journal Title: Cancer Research
Volume: 79
Issue: 13 Suppl.
Meeting Dates: 2019 Mar 29-Apr 3
Meeting Location: Atlanta, GA
ISSN: 0008-5472
Publisher: American Association for Cancer Research  
Date Published: 2019-07-01
Language: English
ACCESSION: WOS:000488129901503
DOI: 10.1158/1538-7445.Sabcs18-329
PROVIDER: wos
Notes: Meeting Abstract: 329 -- Source: Wos
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MSK Authors
  1. Alison Michele Schram
    122 Schram
  2. Helen Hyeong-Eun Won
    109 Won