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Alison Michele Schram

  1. "GSK Faculty"
Formats
  1. Journal Article (26)
  2. Meeting Abstract (24)
  3. Editorial (1)
  4. Research Letter (1)
  5. Review (1)
Groups
  1. Department of Medicine (53)
  2. Early Drug Development Service (53)
  3. GSK Faculty (53)
  4. Gynecologic Medicine Service (53)
  5. Solid Tumor Oncology Division (53)
  6. Human Oncology and Pathogenesis Program (45)

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People
  1. David Hyman (33)
  2. Alexander Drilon (26)
  3. Michael Berger (23)
  4. Barry Taylor (16)
  5. Marc Ladanyi (16)
  6. Ryma Benayed (14)

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Years
  1. 2025 (1)
  2. 2024 (3)
  3. 2023 (3)
  4. 2022 (6)
  5. 2021 (6)
  6. 2020 (10)

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Publications
  1. Journal of Clinical Oncology (10)
  2. Cancer Research (9)
  3. Cancer Discovery (6)
  4. Clinical Cancer Research (5)
  5. Annals of Oncology (3)
  6. Blood (2)

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Publishers
  1. American Association for Cancer Research (21)
  2. American Society of Clinical Oncology (12)
  3. Nature Publishing Group (8)
  4. Oxford University Press (3)
  5. American Society of Hematology (2)
  6. Cell Press (2)

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Results (53)

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  • Restoration of the tumor suppressor function of Y220C-mutant p53 by rezatapopt, a small-molecule reactivator
    Journal Article

    Puzio-Kuter, A. M.; Xu, L.; McBrayer, M. K.; Dominique, R.; Li, H. H.; Fahr, B. J.; Brown, A. M.; Wiebesiek, A. E.; Russo, B. M.; Mulligan, C. L.; more...
    Cancer Discovery (2025)

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  • Histology-specific clinical trial of lenvatinib and pembrolizumab in patients with sarcoma
    Journal Article

    Movva, S.; Seier, K.; Avutu, V.; Banks, L. B.; Chan, J.; Chi, P.; Dickson, M. A.; Gounder, M. M.; Kelly, C. M.; Keohan, M. L.; more...
    Clinical Cancer Research (2024)

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  • CCNE1 amplification as marker of poor prognosis and novel therapeutic target in advanced breast cancer
    Meeting Abstract

    Marra, A.; Selenica, P.; Zhu, Y.; Safonov, A.; Razavi, P.; Roulston, A.; Koehler, M.; Curigliano, G.; Ross, D. S.; Weigelt, B.; more...
    Journal of Clinical Oncology (2024)

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  • Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy
    Journal Article

    Walmsley, C. S.; Jonsson, P.; Cheng, M. L.; McBride, S.; Kaeser, C.; Vargas, H. A.; Laudone, V.; Taylor, B. S.; Kappagantula, R.; Baez, P.; more...
    npj Precision Oncology (2024)

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  • Impact of PARP inhibitor and platinum therapy on clonal hematopoiesis
    Meeting Abstract

    Baeten, J. T.; Chan, I. C. C.; Moukarzel, L.; Carter, A. C.; Patel, M.; Stopsack, K. H.; Pharoah, P.; Brenton, J.; Li, B. T.; Abida, W.; more...
    Blood (2023)

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  • A pilot study of lenvatinib plus pembrolizumab in patients with advanced sarcoma
    Meeting Abstract

    Movva, S.; Avutu, V.; Chi, P.; Dickson, M. A.; Gounder, M. M.; Kelly, Ciara M.; Keohan, M. L.; Meyers, P. A.; Cohen, S. M.; Hensley, M. L.; more...
    Journal of Clinical Oncology (2023)

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  • Genomic characterization of FGFR-altered solid tumors using a clinically annotated pan-cancer repository
    Meeting Abstract

    Choudhury, N. J.; Harada, G.; Whiting, K.; Shen, R.; Yang, S. R.; Solit, D. B.; Berger, M. F.; Dinapoli, S.; Abou-Alfa, G. K.; Iyer, G.; more...
    Journal of Clinical Oncology (2023)

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  • A pilot study of lenvatinib plus pembrolizumab in patients with advanced sarcoma
    Meeting Abstract

    Movva, S.; Avutu, V.; Chi, P.; Dickson, M. A.; Gounder, M. M.; Kelly, C. M.; Keohan, M. L.; Nacev, B. A.; Rosenbaum, E.; Thornton, K. A.; more...
    Journal of Clinical Oncology (2022)

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  • Clinicopathologic characterization of ERK2 E322K mutation in solid tumors: Implications for treatment and drug development
    Meeting Abstract

    Liu, D.; Murciano-Goroff, Y. R.; Jee, J.; Arcila, M. E.; Buonocore, D. J.; Gao, J.; Chakravarty, D.; Schram, A. M.; Callahan, M. K.; Friedman, C. F.; more...
    Journal of Clinical Oncology (2022)

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  • The bi-steric mTORC1-selective inhibitor RMC-5552 in tumors with activation of mTOR signaling: Preclinical activity in combination with RAS(ON) inhibitors in RAS-addicted tumors, and initial clinical findings from a single agent phase 1/1b study
    Meeting Abstract

    Burris, H. A. 3rd; Ulahannan, S. V.; Haura, E. B.; Ou, S. H. I.; Capasso, A.; Munster, P. N.; Kitai, H.; Wang, Z.; Hayes, J.; Tao, L.; more...
    Journal of Clinical Oncology (2022)

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