The bi-steric mTORC1-selective inhibitor RMC-5552 in tumors with activation of mTOR signaling: Preclinical activity in combination with RAS(ON) inhibitors in RAS-addicted tumors, and initial clinical findings from a single agent phase 1/1b study Meeting Abstract


Authors: Burris, H. A. 3rd; Ulahannan, S. V.; Haura, E. B.; Ou, S. H. I.; Capasso, A.; Munster, P. N.; Kitai, H.; Wang, Z.; Hayes, J.; Tao, L.; Wong, S.; Yang, Y. C.; Jiang, J. J.; Bitman, B.; Singh, M.; Gustafson, W. C.; Rosen, N.; Schram, A. M.
Abstract Title: The bi-steric mTORC1-selective inhibitor RMC-5552 in tumors with activation of mTOR signaling: Preclinical activity in combination with RAS(ON) inhibitors in RAS-addicted tumors, and initial clinical findings from a single agent phase 1/1b study
Meeting Title: 2022 ASCO Annual Meeting
Journal Title: Journal of Clinical Oncology
Volume: 40
Issue: 16 Suppl.
Meeting Dates: 2022 Jun 3-7
Meeting Location: Chicago, IL
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2022-06-01
Language: English
ACCESSION: WOS:000863680300991
PROVIDER: wos
DOI: 10.1200/JCO.2022.40.16_suppl.3098
Notes: Meeting Abstract: 3098 -- This meeting was also held virtually -- Source: Wos
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  1. Neal Rosen
    425 Rosen
  2. Alison Michele Schram
    122 Schram
  3. Hidenori Kitai
    3 Kitai