Research Focus

Former Employee. Graduate Staff; Fellow

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1. The immunomodulatory protein Dickkopf-1 (DKK1) defines a non-neuroendocrine subtype of metastatic castration-resistant prostate cancer (mCRPC) with low AR and low PSA expression

   Meeting Abstract

   Wise, D.; Armenia, J.; Chen, Y.; Nelson, P.; Schultz, N.; Sawyers, C. L.; Scher, H. I.
   Journal of Clinical Oncology (2017)

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2. Androgen receptor pathway-independent prostate cancer is sustained through FGF signaling

   Journal Article

   Bluemn, E. G.; Coleman, I. M.; Lucas, J. M.; Coleman, R. T.; Hernandez-Lopez, S.; Tharakan, R.; Bianchi-Frias, D.; Dumpit, R. F.; Kaipainen, A.; Corella, A. N.; more...
   Cancer Cell (2017)

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3. Hypoxia promotes isocitrate dehydrogenasedependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

   Journal Article

   Wise, D. R.; Ward, P. S.; Shay, J. E. S.; Cross, J. R.; Gruber, J. J.; Sachdeva, U. M.; Platt, J. M.; DeMatteo, R. G.; Simon, M. C.; Thompson, C. B.
   Proceedings of the National Academy of Sciences of the United States of America (2011)

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