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Justin Robert Cross

  1. "Cancer Biology and Genetics Program Faculty"
Formats
  1. Journal Article (27)
  2. Meeting Abstract (5)
  3. Research Letter (1)
Groups
  1. Cancer Biology and Genetics Program Faculty (33)
  2. GSK Faculty (33)
  3. Sloan Kettering Institute Faculty (33)
  4. Center for Hematologic Malignancies (31)
  5. Center for Molecular Imaging and Biotechnology (CMIB) (31)
  6. Hematologic Malignancies Research (30)

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People
  1. Craig Thompson (27)
  2. Lydia Finley (7)
  3. Chao Lu (6)
  4. Andrew Intlekofer (5)
  5. Hui Liu (5)
  6. Sriram Venneti (5)

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Years
  1. 2025 (2)
  2. 2024 (1)
  3. 2022 (2)
  4. 2021 (1)
  5. 2020 (4)
  6. 2019 (2)

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Publications
  1. Nature (4)
  2. Blood (3)
  3. Cell Metabolism (3)
  4. Proceedings of the National Academy of Sciences of the United States of America (3)
  5. Cancer Cell (2)
  6. Cancer Discovery (2)

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Publishers
  1. Nature Publishing Group (9)
  2. American Association for Cancer Research (3)
  3. American Society of Hematology (3)
  4. Cell Press (3)
  5. Elsevier Inc. (3)
  6. National Academy of Sciences (3)

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Results (33)

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  • α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia
    Journal Article

    Millman, S. E.; Chaves-Perez, A.; Janaki-Raman, S.; Ho, Y. J.; Morris, J. P. 4th; Narendra, V.; Chen, C. C.; Jackson, B. T.; Yashinskie, J. J.; Mezzadra, R.; more...
    Blood (2025)

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  • Metabolic engineering to facilitate anti-tumor immunity
    Journal Article

    Schild, T.; Wallisch, P.; Zhao, Y.; Wang, Y. T.; Haughton, L.; Chirayil, R.; Pierpont, K.; Chen, K.; Nunes-Violante, S.; Cross, J.; more...
    Cancer Cell (2025)

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  • Cellular ATP demand creates metabolically distinct subpopulations of mitochondria
    Journal Article

    Ryu, K. W.; Fung, T. S.; Baker, D. C.; Saoi, M.; Park, J.; Febres-Aldana, C. A.; Aly, R. G.; Cui, R.; Sharma, A.; Fu, Y.; more...
    Nature (2024)

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  • OGDH Is a genetic vulnerability and therapeutic target in acute myeloid leukemia
    Meeting Abstract

    Millman, S. E.; Chaves-Perez, A.; Morris, J. P. 4th; Chen, C. C.; Ho, Y. J.; Raman, S. J.; Yashinskie, J. J.; Mezzadra, R.; Narendra, V.; Tian, S.; more...
    Blood (2022)

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  • Hyperpolarized [5-(13)C,4,4-(2)H(2),5-(15)N]-L-glutamine provides a means of annotating in vivo metabolic utilization of glutamine
    Journal Article

    Eskandari, R.; Kim, N.; Mamakhanyan, A.; Saoi, M.; Zhang, G.; Berisaj, M.; Granlund, K. L.; Poot, A. J.; Cross, J.; Thompson, C. B.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2022)

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  • Mitochondrial NADP(H) generation is essential for proline biosynthesis
    Research Letter

    Zhu, J.; Schwörer, S.; Berisa, M.; Kyung, Y. J.; Ryu, K. W.; Yi, J.; Jiang, X.; Cross, J. R.; Thompson, C. B.
    Science (2021)

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  • Translation in amino-acid-poor environments is limited by tRNA(Gln) charging
    Journal Article

    Pavlova, N. N.; King, B.; Josselsohn, R. H.; Violante, S.; Macera, V. L.; Vardhana, S. A.; Cross, J. R.; Thompson, C. B.
    eLife (2020)

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  • Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen
    Journal Article

    Vardhana, S. A.; Hwee, M. A.; Berisa, M.; Wells, D. K.; Yost, K. E.; King, B.; Smith, M.; Herrera, P. S.; Chang, H. Y.; Satpathy, A. T.; more...
    Nature Immunology (2020)

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  • Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress
    Journal Article

    Schwörer, S.; Berisa, M.; Violante, S.; Qin, W.; Zhu, J.; Hendrickson, R. C.; Cross, J. R.; Thompson, C. B.
    EMBO Journal (2020)

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  • Vitamin B6 addiction in acute myeloid leukemia
    Journal Article

    Chen, C. C.; Li, B.; Millman, S. E.; Chen, C.; Li, X.; Morris, J. P. 4th; Mayle, A.; Ho, Y. J.; Loizou, E.; Liu, H.; more...
    Cancer Cell (2020)

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