Synapse - Bayard Clarkson

Results (220)

Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Journal Article

Nagar, B.; Bornmann, W. G.; Pellicena, P.; Schindler, T.; Veach, D. R.; Miller, W. T.; Clarkson, B.; Kuriyan, J.
Cancer Research (2002)

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Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases

Journal Article

Wisniewski, D.; Lambek, C. L.; Liu, C.; Strife, A.; Veach, D. R.; Nagar, B.; Young, M. A.; Schindler, T.; Bornmann, W. G.; Bertino, J. R.; more...
Cancer Research (2002)

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Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling

Journal Article

Liang, X.; Wisniewski, D.; Strife, A.; Shivakrupa; Clarkson, B.; Resh, M. D.
Journal of Biological Chemistry (2002)

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Crystal structures of the c-Abl tyrosine kinase domain in complex with STI-571 and a novel Bcr-Abl inhibitor, PD173955

Meeting Abstract

Swendeman, S.; Nagar, B.; Wisniewski, D.; Strife, A.; Lambek, C.; Liu, C.; Veach, D.; Bornmann, W.; Kuriyan, J.; Clarkson, B.
Clinical Cancer Research (2001)

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p62dok, a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210bcr-abl

Journal Article

Di Cristofano, A.; Niki, M.; Zhao, M.; Karnell, F. G.; Clarkson, B.; Pear, W. S.; Van Aelst, L.; Pandolfi, P. P.
Journal of Experimental Medicine (2001)

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Characterization of two novel sublines established from a human megakaryoblastic leukemia cell line transfected with p210(BCR-ABL)

Journal Article

Berman, E.; Jhanwar, S.; McBride, M.; Strife, A.; Wisniewski, D.; Lambek, C.; Clarkson, B.
Leukemia Research (2000)

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Structural mechanism for the inhibition of Abelson tyrosine kinase by a small molecule inhibitor that is effective in the treatment of chronic myelogenous leukemia

Meeting Abstract

Schindler, T.; Vidal, E.; Bornmann, W. G.; Pellicena, P.; Miller, W. T.; Clarkson, B.; Kuriyan, J.
Clinical Cancer Research (2000)

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Role of p65(dok) in leukemogenesis by p210(bcr-abl)

Meeting Abstract

Niki, M.; Di Cristofano, A.; Zhao, M.; Karnell, F. G.; Clarkson, B.; Pear, W. S.; Van Aelst, L.; Pandolfi, P. P.
Blood (2000)

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Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase

Journal Article

Schindler, T.; Bornmann, W.; Pellicena, P.; Miller, W. T.; Clarkson, B.; Kuriyan, J.
Science (2000)

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The phosphatidylinositol polyphosphate 5-phosphatase SHIP1 associates with the Dok1 phosphoprotein in Bcr-Abl transformed cells

Journal Article

Dunant, N. M.; Wisniewski, D.; Strife, A.; Clarkson, B.; Resh, M. D.
Cellular Signalling (2000)

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