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Alan N Houghton

Formats
  1. Journal Article (227)
  2. Meeting Abstract (104)
  3. Book Section (24)
  4. Book Whole (5)
  5. Conference Paper (4)
Groups
  1. Immunology Program Faculty (364)
  2. Sloan Kettering Institute Faculty (364)
  3. Department of Medicine (226)
  4. Solid Tumor Oncology Division (194)
  5. Melanoma and Immunotherapeutics Service (179)
  6. GSK Faculty (158)

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People
  1. Jedd Wolchok (118)
  2. Paul Chapman (60)
  3. Taha Merghoub (45)
  4. Jonathan Lewis (35)
  5. Katherine Panageas (29)
  6. Miguel-Angel Perales (29)

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Years
  1. 2022 (2)
  2. 2021 (1)
  3. 2017 (1)
  4. 2014 (1)
  5. 2013 (10)
  6. 2012 (4)

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Publications
  1. Proceedings of the American Association for Cancer Research Annual Meeting (30)
  2. Cancer Research (26)
  3. Clinical Cancer Research (23)
  4. Journal of Experimental Medicine (18)
  5. Blood (15)
  6. Journal of Immunology (15)

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Publishers
  1. American Association for Cancer Research (80)
  2. Elsevier Inc. (26)
  3. Elsevier Science, Inc. (20)
  4. Rockefeller University Press (19)
  5. Wiley Blackwell (16)
  6. American Society of Hematology (15)

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Results (364)

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  • Immune checkpoint blockade enhances cyclophosphamide induced anti-tumor immunity in a preclinical melanoma model
    Meeting Abstract

    George, M.; Betof, A.; Merghoub, T.; Hamadene, L.; Hirschhorn, D.; Houghton, A.; Wolchok, J.
    Journal for ImmunoTherapy of Cancer (2022)

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  • Combination of cyclophosphamide with immune checkpoint blockade inhibition elicits potent tumor control in a preclinical melanoma model
    Meeting Abstract

    George, M. M.; Warner, A. B.; Hamadene, L.; Hirschhorn, D.; Houghton, A. N.; Wolchok, J. D.; Merghoub, T.
    Cancer Research (2022)

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  • Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness
    Journal Article

    Hirschhorn, D.; Betof Warner, A.; Maniyar, R.; Chow, A.; Mangarin, L. M. B.; Cohen, A. D.; Hamadene, L.; Rizzuto, G. A.; Budhu, S.; Suek, N.; more...
    JCI Insight (2021)

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  • Blockade of surface-bound TGF-ß on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment
    Journal Article

    Budhu, S.; Schaer, D. A.; Li, Y.; Toledo-Crow, R.; Panageas, K.; Yang, X.; Zhong, H.; Houghton, A. N.; Silverstein, S. C.; Merghoub, T.; more...
    Science Signaling (2017)

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  • Blockade of surface bound TGF-β abrogates Treg suppression of effector T cell function within the tumor microenvironment
    Meeting Abstract

    Budhu, S.; Schaer, D.; Li, Y.; Houghton, A.; Silverstein, S.; Merghoub, T.; Wolchok, J. D.
    Journal for ImmunoTherapy of Cancer (2014)

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  • Blockade of Treg derived TGF-β abrogates suppression of effector T cell function within the tumor microenvironment
    Meeting Abstract

    Budhu, S.; Schaer, D.; Li, Y.; Houghton, A.; Silverstein, S.; Merghoub, T.; Wolchok, J.
    Journal for ImmunoTherapy of Cancer (2013)

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  • Immunologic responses to xenogeneic tyrosinase DNA vaccine administered by electroporation in patients with malignant melanoma
    Journal Article

    Yuan, J.; Ku, G. Y.; Adamow, M.; Mu, Z.; Tandon, S.; Hannaman, D.; Chapman, P.; Schwartz, G.; Carvajal, R.; Panageas, K. S.; more...
    Journal for ImmunoTherapy of Cancer (2013)

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  • Therapeutic efficacy of antitumor monoclonal antibodies combined with chemotherapy depends on innate immunity and NK1.1-innate lymphoid cells
    Meeting Abstract

    Moskalenko, M.; Pan, M.; Hashimoto, D.; Mortha, A.; Bernardo, S. G.; Leboeuf, M.; Houghton, A.; Wolchok, J.; Burakoff, S.; Merad, M.; more...
    Cancer Research (2013)

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  • GITR pathway activation abrogates tumor immune suppression through loss of regulatory T-cell lineage stability
    Journal Article

    Schaer, D. A.; Budhu, S.; Liu, C.; Bryson, C.; Malandro, N.; Cohen, A.; Zhong, H.; Yang, X.; Houghton, A. N.; Merghoub, T.; more...
    Cancer Immunology Research (2013)

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  • Enhanced responses to tumor immunization following total body irradiation are time-dependent
    Journal Article

    Diab, A.; Jenq, R. R.; Rizzuto, G. A.; Cohen, A. D.; Huggins, D. W.; Merghoub, T.; Engelhorn, M. E.; Guevara-Patiño, J. A.; Suh, D.; Hubbard-Lucey, V. M.; more...
    PLoS ONE (2013)

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