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Gavril W Pasternak

  1. "Amanda Hunkele"
Formats
  1. Journal Article (15)
Groups
  1. Molecular Pharmacology and Chemistry Program Faculty (15)
  2. Sloan Kettering Institute Faculty (15)
  3. Sloan Kettering Institute Postdocs (6)
  4. Anesthesiology Service (2)
  5. Anesthesiology and Critical Care Medicine (2)
People
  1. Amanda Hunkele (15)
  2. Valerie Le Rouzic (11)
  3. Yingxian Pan (11)
  4. Jin Xu (8)
  5. Susruta Majumdar (8)
  6. Ankita Narayan (5)

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Years
  1. 2021 (5)
  2. 2019 (3)
  3. 2018 (1)
  4. 2017 (2)
  5. 2016 (2)
  6. 2015 (2)
Publications
  1. ACS Chemical Neuroscience (4)
  2. Cellular and Molecular Neurobiology (2)
  3. Journal of Medicinal Chemistry (2)
  4. Anesthesia and Analgesia (1)
  5. Journal of Clinical Investigation (1)
  6. MedChemComm (1)

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Publishers
  1. American Chemical Society (6)
  2. Springer (2)
  3. American Society for Clinical Investigation (1)
  4. Lippincott Williams & Wilkins (1)
  5. Pergamon-Elsevier Science Ltd (1)
  6. Public Library of Science (1)

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Results (15)

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  • Oxidative metabolism as a modulator of kratom's biological actions
    Journal Article

    Chakraborty, S.; Uprety, R.; Slocum, S. T.; Irie, T.; Le Rouzic, V.; Li, X.; Wilson, L. L.; Scouller, B.; Alder, A. F.; Kruegel, A. C.; more...
    Journal of Medicinal Chemistry (2021)

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  • Kratom alkaloids as probes for opioid receptor function: Pharmacological characterization of minor indole and oxindole alkaloids from kratom
    Journal Article

    Chakraborty, S.; Uprety, R.; Daibani, A. E.; Rouzic, V. L.; Hunkele, A.; Appourchaux, K.; Eans, S. O.; Nuthikattu, N.; Jilakara, R.; Thammavong, L.; more...
    ACS Chemical Neuroscience (2021)

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  • Synthesis and characterization of azido aryl analogs of IBNtxA for radio-photoaffinity labeling opioid receptors in cell lines and in mouse brain
    Journal Article

    Grinnell, S. G.; Uprety, R.; Varadi, A.; Subrath, J.; Hunkele, A.; Pan, Y. X.; Pasternak, G. W.; Majumdar, S.
    Cellular and Molecular Neurobiology (2021)

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  • Mu opioids induce biased signaling at the full-length seven transmembrane C-terminal splice variants of the mu opioid receptor gene, Oprm1
    Journal Article

    Narayan, A.; Hunkele, A.; Xu, J.; Bassoni, D. L.; Pasternak, G. W.; Pan, Y. X.
    Cellular and Molecular Neurobiology (2021)

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  • Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
    Journal Article

    Uprety, R.; Che, T.; Zaidi, S. A.; Grinnell, S. G.; Varga, B. R.; Faouzi, A.; Slocum, S. T.; Allaoa, A.; Varadi, A.; Nelson, M.; more...
    eLife (2021)

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  • Identification of abundant and evolutionarily conserved opioid receptor circular RNAs in the nervous system modulated by morphine
    Journal Article

    Irie, T.; Shum, R.; Deni, I.; Hunkele, A.; Le Rouzic, V.; Xu, J.; Wilson, R.; Fischer, G. W.; Pasternak, G. W.; Pan, Y. X.
    Molecular Pharmacology (2019)

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  • Kinetic and thermodynamic insights into sodium ion translocation through the μ-opioid receptor from molecular dynamics and machine learning analysis
    Journal Article

    Hu, X.; Wang, Y.; Hunkele, A.; Provasi, D.; Pasternak, G. W.; Filizola, M.
    PLoS Computational Biology (2019)

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  • Pharmacological characterization of levorphanol, a G-protein biased opioid analgesic
    Journal Article

    Le Rouzic, V.; Narayan, A.; Hunkle, A.; Marrone, G. F.; Lu, Z.; Majumdar, S.; Xu, J.; Pan, Y. X.; Pasternak, G. W.
    Anesthesia and Analgesia (2019)

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  • Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace
    Journal Article

    Baumann, M. H.; Majumdar, S.; Le Rouzic, V.; Hunkele, A.; Uprety, R.; Huang, X. P.; Xu, J.; Roth, B. L.; Pan, Y. X.; Pasternak, G. W.
    Neuropharmacology (2018)

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  • Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine
    Journal Article

    Xu, J.; Lu, Z.; Narayan, A.; Le Rouzic, V. P.; Xu, M.; Hunkele, A.; Brown, T. G.; Hoefer, W. F.; Rossi, G. C.; Rice, R. C.; more...
    Journal of Clinical Investigation (2017)

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