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Gavril W Pasternak

  1. "Sloan Kettering Institute Postdocs"
Formats
  1. Journal Article (30)
  2. Meeting Abstract (5)
Groups
  1. Molecular Pharmacology and Chemistry Program Faculty (35)
  2. Sloan Kettering Institute Faculty (35)
  3. Sloan Kettering Institute Postdocs (35)
  4. GSK Faculty (2)
  5. Anesthesiology Service (1)
  6. Anesthesiology and Critical Care Medicine (1)

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People
  1. Susruta Majumdar (18)
  2. Yingxian Pan (16)
  3. Jin Xu (12)
  4. Valerie Le Rouzic (12)
  5. Andras Varadi (11)
  6. Rajendra Uprety (10)

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Years
  1. 2023 (1)
  2. 2021 (4)
  3. 2020 (2)
  4. 2019 (3)
  5. 2018 (2)
  6. 2017 (1)

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Publications
  1. Abstracts of Papers of the American Chemical Society (3)
  2. Neuropharmacology (3)
  3. Proceedings of the National Academy of Sciences of the United States of America (3)
  4. ACS Chemical Neuroscience (2)
  5. European Journal of Medicinal Chemistry (2)
  6. ACS Central Science (1)

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Publishers
  1. American Chemical Society (8)
  2. Elsevier Inc. (4)
  3. National Academy of Sciences (3)
  4. Pergamon-Elsevier Science Ltd (3)
  5. Cell Press (2)
  6. Society for Neuroscience (2)

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Results (35)

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  • Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy
    Journal Article

    Majd, H.; Amin, S.; Ghazizadeh, Z.; Cesiulis, A.; Arroyo, E.; Lankford, K.; Majd, A.; Farahvashi, S.; Chemel, A. K.; Okoye, M.; more...
    Cell Stem Cell (2023)

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  • Oxidative metabolism as a modulator of kratom's biological actions
    Journal Article

    Chakraborty, S.; Uprety, R.; Slocum, S. T.; Irie, T.; Le Rouzic, V.; Li, X.; Wilson, L. L.; Scouller, B.; Alder, A. F.; Kruegel, A. C.; more...
    Journal of Medicinal Chemistry (2021)

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  • Kratom alkaloids as probes for opioid receptor function: Pharmacological characterization of minor indole and oxindole alkaloids from kratom
    Journal Article

    Chakraborty, S.; Uprety, R.; Daibani, A. E.; Rouzic, V. L.; Hunkele, A.; Appourchaux, K.; Eans, S. O.; Nuthikattu, N.; Jilakara, R.; Thammavong, L.; more...
    ACS Chemical Neuroscience (2021)

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  • Synthesis and characterization of azido aryl analogs of IBNtxA for radio-photoaffinity labeling opioid receptors in cell lines and in mouse brain
    Journal Article

    Grinnell, S. G.; Uprety, R.; Varadi, A.; Subrath, J.; Hunkele, A.; Pan, Y. X.; Pasternak, G. W.; Majumdar, S.
    Cellular and Molecular Neurobiology (2021)

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  • Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
    Journal Article

    Uprety, R.; Che, T.; Zaidi, S. A.; Grinnell, S. G.; Varga, B. R.; Faouzi, A.; Slocum, S. T.; Allaoa, A.; Varadi, A.; Nelson, M.; more...
    eLife (2021)

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  • Imaging sigma-1 receptor (S1R) expression using iodine-124-labeled 1-(4-iodophenyl)-3-(2-adamantyl)guanidine ([(124)I]IPAG)
    Journal Article

    Gangangari, K. K.; Váradi, A.; Majumdar, S.; Larson, S. M.; Pasternak, G. W.; Pillarsetty, N. V. K.
    Molecular Imaging and Biology (2020)

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  • G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder
    Journal Article

    Gutridge, A. M.; Robins, M. T.; Cassell, R. J.; Uprety, R.; Mores, K. L.; Ko, M. J.; Pasternak, G. W.; Majumdar, S.; van Rijn, R. M.
    British Journal of Pharmacology (2020)

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  • 7-hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects
    Journal Article

    Kruegel, A. C.; Uprety, R.; Grinnell, S. G.; Langreck, C.; Pekarskaya, E. A.; Le Rouzic, V.; Ansonoff, M.; Gassaway, M. M.; Pintar, J. E.; Pasternak, G. W.; more...
    ACS Central Science (2019)

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  • MP1104, a mixed kappa-delta opioid receptor agonist has anti-cocaine properties with reduced side-effects in rats
    Journal Article

    Atigari, D. V.; Uprety, R.; Pasternak, G. W.; Majumdar, S.; Kivell, B. M.
    Neuropharmacology (2019)

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  • Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ1) receptor selective ligands
    Journal Article

    Uprety, R.; Váradi, A.; Allaoa, A.; Redel-Traub, G. N.; Palmer, T. C.; Feinberg, E. N.; Ferris, A. C.; Pande, V. S.; Pasternak, G. W.; Majumdar, S.
    European Journal of Medicinal Chemistry (2019)

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