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Christina Leslie

  1. "Computational and Structural Biology Program Faculty"
Formats
  1. Journal Article (33)
  2. Meeting Abstract (8)
  3. Conference Paper (1)
  4. Review (1)
Groups
  1. Center for Molecular Imaging and Biotechnology (CMIB) (43)
  2. Computational and Structural Biology Program Faculty (43)
  3. GSK Faculty (43)
  4. Sloan Kettering Institute Faculty (43)
  5. Sloan Kettering Institute Postdocs (31)
  6. MSK Grad Students (26)

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People
  1. Ming Li (8)
  2. Alexander Rudensky (7)
  3. Briana Nixon (5)
  4. Eneda Toska (5)
  5. Hatice Osmanbeyoglu (5)
  6. Kristelle Capistrano (5)

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Years
  1. 2025 (2)
  2. 2024 (5)
  3. 2023 (4)
  4. 2022 (5)
  5. 2021 (3)
  6. 2020 (2)

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Publications
  1. Blood (3)
  2. Cell Reports (3)
  3. Immunity (3)
  4. Nature Communications (3)
  5. Cancer Research (2)
  6. Genome Biology (2)

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Publishers
  1. Nature Publishing Group (14)
  2. Cell Press (10)
  3. American Society of Hematology (3)
  4. American Association for Cancer Research (2)
  5. American Association for the Advancement of Science (2)
  6. Biomed Central Ltd (2)

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Results (43)

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  • Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2
    Journal Article

    Schmidt, H.; Zhang, M.; Chakarov, D.; Bansal, V.; Mourelatos, H.; Sánchez-Rivera, F. J.; Lowe, S. W.; Ventura, A.; Leslie, C. S.; Pritykin, Y.
    Genome Biology (2025)

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  • CD4+ T-cell lymphoma harboring a chimeric antigen receptor integration in TP53
    Journal Article

    Perica, K.; Jain, N.; Scordo, M.; Patel, R.; Eren, O. C.; Patel, U.; Gundem, G.; Domenico, D.; Mitra, S.; Socci, N. D.; more...
    New England Journal of Medicine (2025)

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  • A single-cell atlas of classical mantle cell lymphoma reveals paired tumor-immune malignant states correlating with prognosis
    Meeting Abstract

    Marouf, A.; Mitra, S.; Isgor, I.; Joseph, A.; Rahman, J.; Lin, Y. H.; Takizawa, M.; Chaligne, R.; Sethi, S.; Dogan, A.; more...
    Blood (2024)

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  • Rheumatoid arthritis synovial fibroblast modulation of T cell activation
    Meeting Abstract

    Romoff, M.; Gao, V.; Di Carlo, E.; Ramirez, D.; Goodman, S.; Norman, T.; Leslie, C.; Rudensky, A.; Donlin, L.; Smith, M.
    Journal of Immunology (2024)

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  • CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
    Journal Article

    Kaplan, S. J.; Wong, W.; Yan, J.; Pulecio, J.; Cho, H. S.; Li, Q.; Zhao, J.; Leslie-Iyer, J.; Kazakov, J.; Murphy, D.; more...
    Cell Reports (2024)

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  • Single-cell multi-ome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis
    Journal Article

    Mitra, S.; Malik, R.; Wong, W.; Rahman, A.; Hartemink, A. J.; Pritykin, Y.; Dey, K. K.; Leslie, C. S.
    Nature Genetics (2024)

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  • Comprehensive immunogenomic evaluation of patients undergoing consolidative cytoreductive nephrectomy in metastatic renal cell carcinoma patients treated with immune checkpoint blockade
    Meeting Abstract

    Reese, S.; Yarlagadda, V.; Wu, C. Y.; Kuo, F.; Tang, C.; Jiang, H.; Vuong, L. H.; Eismann, L.; Motzer, R.; Voss, M. H.; more...
    Urologic Oncology: Seminars and Original Investigations (2024)

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  • Low CD117 expression identifies hematopoietic stem cell subsets with enhanced lymphoid potential in mice and humans
    Meeting Abstract

    Elias, H. K.; Mitra, S.; Gipson, B.; da Silva, M. B.; Lee, N.; Ali, M. A. E.; Grassman, S.; Kousa, A.; DeWolf, S.; Park, C. Y.; more...
    Blood (2023)

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  • Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis
    Journal Article

    Do, M. H.; Shi, W.; Ji, L.; Ladewig, E.; Zhang, X.; Srivastava, R. M.; Capistrano, K. J.; Edwards, C.; Malik, I.; Nixon, B. G.; more...
    Immunity (2023)

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  • Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project
    Review

    Dekker, J.; Alber, F.; Aufmkolk, S.; Beliveau, B. J.; Bruneau, B. G.; Belmont, A. S.; Bintu, L.; Boettiger, A.; Calandrelli, R.; Disteche, C. M.; more...
    Molecular Cell (2023)

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