Synapse - Elisa De Stanchina

Results (348)

Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma

Journal Article

Long, A. W.; Xu, H.; Santich, B. H.; Guo, H.; Hoseini, S. S.; de Stanchina, E.; Cheung, N. K. V.
Journal of Hematology & Oncology (2024)

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Combined RAF and MEK inhibition to treat activated non-V600 BRAF-altered advanced cancers

Journal Article

Rustgi, N.; Maria, A.; Toumbacaris, N.; Zhao, H.; Kargus, K.; Bryant, M.; Waksmundzki, A.; Aricescu, I.; Lefkowitz, R. A.; Li, B. T.; more...
The Oncologist (2024)

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A druggable FOXA1-glucocorticoid receptor transcriptional axis drives tumor growth in a subset of non-small cell lung cancer

Journal Article

Dorso, M.; Patel, P. T.; Pankov, A.; Boyer, J. A.; Soni, R. K.; Del Priore, I. S.; Hayatt, O.; Kulick, A.; Hagen, C. J.; de Stanchina, E.; more...
Cancer Research Communications (2023)

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CDC7 inhibition constrains lineage plasticity and prevents resistance and neuroendocrine transformation in the lung and prostate

Meeting Abstract

Quintanal-Villalonga, Á.; Zaidi, S.; Karthaus, W. R.; Zhan, Y. A.; Shafer, M.; Qiu, J.; de Stanchina, E.; Haffner, M. C.; Sawyers, C. L.; Rudin, C. M.
Annals of Oncology (2023)

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Cooperative CAR targeting to selectively eliminate AML and minimize escape

Journal Article

Haubner, S.; Mansilla-Soto, J.; Nataraj, S.; Kogel, F.; Chang, Q.; de Stanchina, E.; Lopez, M.; Ng, M. R.; Fraser, K.; Subklewe, M.; more...
Cancer Cell (2023)

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Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations

Journal Article

Miyazaki, I.; Odintsov, I.; Ishida, K.; Lui, A. J. W.; Kato, M.; Suzuki, T.; Zhang, T.; Wakayama, K.; Kurth, R. I.; Cheng, R.; more...
Nature Cancer (2023)

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De novo and histologically transformed small-cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways

Journal Article

Chakraborty, S.; Coleman, C.; Manoj, P.; Demircioglu, D.; Shah, N.; de Stanchina, E.; Rudin, C. M.; Hasson, D.; Sen, T.
Clinical Cancer Research (2023)

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Combination therapy with MDM2 and MEK inhibitors is effective in patient-derived models of lung adenocarcinoma with concurrent oncogenic drivers and MDM2 amplification

Journal Article

Elkrief, A.; Odintsov, I.; Markov, V.; Caeser, R.; Sobczuk, P.; Tischfield, S. E.; Bhanot, U.; Vanderbilt, C. M.; Cheng, E. H.; Drilon, A.; more...
Journal of Thoracic Oncology (2023)

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Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers

Journal Article

Quintanal-Villalonga, A.; Durani, V.; Sabet, A.; Redin, E.; Kawasaki, K.; Shafer, M.; Karthaus, W. R.; Zaidi, S.; Zhan, Y. A.; Manoj, P.; more...
Science Translational Medicine (2023)

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EZH2 inhibition remodels the inflammatory senescence-associated secretory phenotype to potentiate pancreatic cancer immune surveillance

Journal Article

Chibaya, L.; Murphy, K. C.; DeMarco, K. D.; Gopalan, S.; Liu, H.; Parikh, C. N.; Lopez-Diaz, Y.; Faulkner, M.; Li, J.; Morris, J. P. 4th; more...
Nature Cancer (2023)

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