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Annamalai Selvakumar

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Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1(+) leukemias

Journal Article

Doubrovina, E.; Carpenter, T.; Pankov, D.; Selvakumar, A.; Hasan, A.; O'Reilly, R. J.
Blood (2012)

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CMV-specific T-cells are more effective than WT-1-specific T-cells in eradicating clonogenic tumor cells co-expressing CMVpp65 and WT-1 in-vivo and both types of T-cells are functionally augmented in the presence of IL-15/IL-15R alpha

Meeting Abstract

Hasan, A.; Bakalar, D.; Selvakumar, A.; Koo, G. C.; Doubrovina, E.; Kuo, T. Y.; O'Reilly, R. J.
Blood (2011)

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Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome

Journal Article

Taylor, M. D.; Sadhukhan, S.; Kottangada, P.; Ramgopal, A.; Sarkar, K.; D'Silva, S.; Selvakumar, A.; Candotti, F.; Vyas, Y. M.
Science Translational Medicine (2010)

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Generation of T cells of desired HLA restriction specific for epitopes of a self-antigen, WT1, for the adoptive immunotherapy of WT1 positive malignancies using a panel of artificial antigen presenting cells expressing prevalent HLA alleles

Meeting Abstract

Doubrovina, E.; Hasan, A.; Oflaz-Sozmen, B.; Selvakumar, A.; Sadelain, M. W.; O'Reilly, R. J.
Blood (2009)

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Human colon carcinoma cells expressing CMVpp65 antigen: An in-vivo model for adoptive immunotherapy of CMV disease

Meeting Abstract

Hasan, A. N.; Koo, G. C.; Selvakumar, A.; Kollen, W.; O'Reilly, R. J.
Biology of Blood and Marrow Transplantation (2009)

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Artificial antigen presenting cells that express prevalent HLA alleles: A step towards the broad application of antigen-specific adoptive cell therapies

Journal Article

Hasan, A. N.; Selvakumar, A.; Doubrovina, E.; Riviere, I.; Sadelain, M. W.; O'Reilly, R. J.
Discovery Medicine (2009)

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A panel of artificial APCs expressing prevalent HLA alleles permits generation of cytotoxic T cells specific for both dominant and subdominant viral epitopes for adoptive therapy

Journal Article

Hasan, A. N.; Kollen, W. J.; Trivedi, D.; Selvakumar, A.; Dupont, B.; Sadelain, M.; O'Reilly, R. J.
Journal of Immunology (2009)

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IL-15 augments in-vitro expansion and functional activity of antigen-specific effector memory T-cells (T(EM)) while co-expression of IL-15 and IL-15 R alpha on antigen presenting cells also promotes expansion of central memory T-cells (T(CM))

Meeting Abstract

Hasan, A.; Selvakumar, A.; Dupont, B.; Sadelain, M.; Riviere, I.; O'Reilly, R. J.
Blood (2008)

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Genetic allelic variation in the p53 DNA repair pathway constitute a risk factor for long-term survival in hematopoietic stem cell transplantation

Meeting Abstract

Bojesen, S. E.; Malkki, M.; Gooley, T.; Zhao, L. P.; Selvakumar, A.; Spellman, S. R.; Petersdorf, E. W.; Hansen, J. A.; Dupont, B.
Blood (2008)

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A panel of artificial antigen-presenting cells (AAPC) expressing prevalent HLA alleles permits generation of cytotoxic T cells specific for both subdominant and dominant viral-epitopes for adoptive therapy

Meeting Abstract

Hasan, A.; Kollen, W. J.; Selvakumar, A.; Trivedi, D.; Sadelain, M.; O'Reilly, R. J.
Blood (2007)

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