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Xu Chen

Formats
  1. Journal Article (4)
  2. Meeting Abstract (2)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (4)
  2. Department of Medicine (4)
  3. Division of Subspecialty Medicine (4)
  4. Endocrinology (4)
  5. GSK Faculty (4)
  6. Human Oncology and Pathogenesis Program (4)

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People
  1. James Fagin (4)
  2. Jeffrey Knauf (4)
  3. Linda Johnson (2)
  4. Aime Franco (1)
  5. Boris Bastian (1)
  6. Cristina Montero-Conde (1)

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Years
  1. 2017 (1)
  2. 2014 (2)
  3. 2011 (1)
  4. 2010 (1)
  5. 2009 (1)
Publications
  1. Oncogene (2)
  2. Proceedings of the National Academy of Sciences of the United States of America (2)
  3. Cancer Research (1)
  4. Developmental Biology (1)
Publishers
  1. National Academy of Sciences (2)
  2. Nature Publishing Group (2)
  3. American Association for Cancer Research (1)
  4. Elsevier Inc. (1)

Results (6)

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  • Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene
    Journal Article

    Montero-Conde, C.; Leandro-Garcia, L. J.; Chen, X.; Oler, G.; Ruiz-Llorente, S.; Ryder, M.; Landa, I.; Sanchez-Vega, F.; La, K.; Ghossein, R. A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2017)

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  • Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition
    Journal Article

    Chen, X.; Makarewicz, J. M.; Knauf, J. A.; Johnson, L. K.; Fagin, J. A.
    Oncogene (2014)

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  • Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations
    Journal Article

    Chen, X.; Wu, Q.; Tan, L.; Porter, D.; Jager, M. J.; Emery, C.; Bastian, B. C.
    Oncogene (2014)

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  • The farnesyl transferase inhibitor SCH 66336 induces regression of Hras-driven tumors in mice with widespread endogenous expression of HrasG12V
    Meeting Abstract

    Chen, X.; Johnson, L. K.; Knauf, J. A.; Fagin, J. A.
    Cancer Research (2011)

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  • Gain-of-function in Ras signaling perturbs dental development in mouse and human
    Meeting Abstract

    Goodwin, A.; Oberoi, S.; Charles, C.; Groth, J. C.; Fairley, C. F.; Chen, X.; Fagin, J. A.; Rauen, K. A.; Klein, O. D.
    Developmental Biology (2010)

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  • Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene
    Journal Article

    Chen, X.; Mitsutake, N.; LaPerle, K.; Akeno, N.; Zanzonico, P.; Longo, V. A.; Mitsutake, S.; Kimura, E. T.; Geiger, H.; Santos, E.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2009)

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