Synapse - Eileen O'Reilly

Results (40)

Lynch syndrome and somatic mismatch repair variants in pancreas cancer

Journal Article

O'Connor, C. A.; Harrold, E.; Lin, D.; Walch, H.; Gazzo, A.; Ranganathan, M.; Kane, S.; Keane, F.; Schoenfeld, J.; Moss, D.; more...
JAMA Oncology (2024)

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Somatic mismatch repair deficiency in pancreas cancer (PC): Immune checkpoint blockade (ICB) outcomes and exploratory genomic analyses

Meeting Abstract

O'Connor, C. A.; Harrold, E.; Lin, Y. T.; Walch, H. S.; Gazzo, A.; Kane, S. R.; Keane, F.; Schoenfeld, J. D.; Moss, D.; Suehnholz, S. P.; more...
Journal of Clinical Oncology (2024)

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Genomic profiling reveals germline predisposition and homologous recombination deficiency in pancreatic acinar cell carcinoma

Journal Article

Mandelker, D.; Marra, A.; Zheng-Lin, B.; Selenica, P.; Blanco-Heredia, J.; Zhu, Y.; Gazzo, A.; Wong, D.; Yelskaya, Z.; Rai, V.; more...
Journal of Clinical Oncology (2023)

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Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade

Journal Article

Harrold, E. C.; Foote, M. B.; Rousseau, B.; Walch, H.; Kemel, Y.; Richards, A. L.; Keane, F.; Cercek, A.; Yaeger, R.; Rathkopf, D.; more...
Nature Medicine (2023)

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Clinical and molecular characterization of microsatellite stable (MSS) tumors in patients with Lynch syndrome (LS)

Meeting Abstract

Harrold, E.; Vanderbilt, C.; Maio, A.; Borio, M.; Ranganathan, M.; Sheehan, M.; O'Connor, C.; Murciano-Goroff, Y. R.; Walsh, M. F.; Will, M.; more...
Journal of Clinical Oncology (2023)

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The frequency of second primary malignancies and colonic polyps in Lynch syndrome with MSI tumors following immune checkpoint blockade

Meeting Abstract

Harrold, E.; Patel, Z.; Maio, A.; Cercek, A.; Yaeger, R.; Segal, N. H.; Reidy, D. L.; O'Reilly, E. M.; Desai, A. M.; Carlo, M. I.; more...
Journal of Clinical Oncology (2022)

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Methylation analyses reveal promoter hypermethylation as a rare cause of “second hit” in germline BRCA1-associated pancreatic ductal adenocarcinoma

Journal Article

Zheng-Lin, B.; Rainone, M.; Varghese, A. M.; Yu, K. H.; Park, W.; Berger, M.; Mehine, M.; Chou, J.; Capanu, M.; Mandelker, D.; more...
Molecular Diagnosis and Therapy (2022)

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Comprehensive assessment of germline pathogenic variant detection in tumor-only sequencing

Journal Article

Terraf, P.; Pareja, F.; Brown, D. N.; Ceyhan-Birsoy, O.; Misyura, M.; Rana, S.; O'Reilly, E.; Carlo, M. I.; Aghajanian, C.; Liu, Y.; more...
Annals of Oncology (2022)

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Early-onset pancreas cancer: Clinical descriptors, genomics, and outcomes

Journal Article

Varghese, A. M.; Singh, I.; Singh, R.; Kunte, S.; Chou, J. F.; Capanu, M.; Wong, W.; Lowery, M. A.; Stadler, Z. K.; Salo-Mullen, E.; more...
JNCI: Journal of the National Cancer Institute (2021)

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Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes

Journal Article

Momtaz, P.; O'Connor, C. A.; Chou, J. F.; Capanu, M.; Park, W.; Bandlamudi, C.; Berger, M. F.; Kelsen, D. P.; Suehnholz, S. P.; Chakravarty, D.; more...
Cancer (2021)

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