Synapse - Hakim Djaballah

Results (101)

The FAK inhibitor PF-573228 demonstrates anti-proliferative and anti-invasive activity in MUC16/CA125(+) ovarian carcinoma cells

Meeting Abstract

dos Santos, L. A. ; Diaz, J. P.; Djaballah, H.; Shum, D.; Normand, G.; Ma, X.; Thapi, D.; Yan, X. J.; Rosales, N.; Spriggs, D. R.
Cancer Research (2009)

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Identification and preliminary characterization of novel small molecules that inhibit growth of human lung adenocarcinoma cells

Journal Article

Somwar, R.; Shum, D.; Djaballah, H.; Varmus, H.
Journal of Biomolecular Screening (2009)

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A miniaturized 1536-well format γ-secretase assay

Journal Article

Shelton, C. C.; Tian, Y.; Shum, D.; Radu, C.; Djaballah, H.; Li, Y. M.
Assay and Drug Development Technologies (2009)

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Modulation of γ-secretase specificity using small molecule allosteric inhibitors

Journal Article

Shelton, C. C.; Zhu, L.; Chau, D.; Yang, L.; Wang, R.; Djaballah, H.; Zheng, H.; Li, Y. M.
Proceedings of the National Academy of Sciences of the United States of America (2009)

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Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: Toward selective Abl inhibitors

Journal Article

Antczak, C.; Veach, D. R.; Ramirez, C. N.; Minchenko, M. A.; Shum, D.; Calder, P. A.; Frattini, M. G.; Clarkson, B.; Djaballah, H.
Bioorganic & Medicinal Chemistry Letters (2009)

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Live-cell imaging of caspase activation for high-content screening

Journal Article

Antczak, C.; Takagi, T.; Ramirez, C. N.; Radu, C.; Djaballah, H.
Journal of Biomolecular Screening (2009)

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Revisiting old drugs as novel agents for retinoblastoma: In vitro and in vivo antitumor activity of cardenolides

Journal Article

Antczak, C.; Kloepping, C.; Radu, C.; Genski, T.; Müller-Kuhrt, L.; Siems, K.; de Stanchina, E.; Abramson, D. H.; Djaballah, H.
Investigative Ophthalmology & Visual Science (IOVS) (2009)

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Development and validation of a high-density fluorescence polarization- based assay for the trypanosoma RNA triphosphatase TbCet1

Journal Article

Antczak, C.; Shum, D.; Radu, C.; Seshan, V. E.; Djaballah, H.
Combinatorial Chemistry and High Throughput Screening (2009)

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Small molecule inhibition of Cdc7, a key cell cycle regulator and novel therapeutic target, successfully inhibits leukemia cell growth in vitro and in vivo

Meeting Abstract

Frattini, M. G.; Shum, D.; O'dwyer, K. M.; Brentjens, R. J.; Yeh, R.; Maslak, P.; Heaney, M. L.; Jurcic, J.; Djaballah, H.; Kelly, T. J.
Blood (2008)

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A high density assay format for the detection of novel cytotoxic agents in large chemical libraries

Journal Article

Shum, D.; Radu, C.; Kim, E.; Cajuste, M.; Shao, Y.; Seshan, V. E.; Djaballah, H.
Journal of Enzyme Inhibition and Medicinal Chemistry (2008)

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