Synapse - Yehuda Goldgur

Results (42)

Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: Conformational switches in the kinase upon binding of the GTP phosphate donor

Journal Article

Banerjee, A.; Goldgur, Y.; Schwer, B.; Shuman, S.
Nucleic Acids Research (2019)

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A small-molecule pan-Id antagonist inhibits pathologic ocular neovascularization

Journal Article

Wojnarowicz, P. M.; Lima e Silva, R.; Ohnaka, M.; Lee, S. B.; Chin, Y.; Kulukian, A.; Chang, S. H.; Desai, B.; Garcia Escolano, M.; Shah, R.; more...
Cell Reports (2019)

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Structure of fission yeast transcription factor Pho7 bound to pho1 promoter DNA and effect of Pho7 mutations on DNA binding and phosphate homeostasis

Journal Article

Garg, A.; Goldgur, Y.; Sanchez, A. M.; Schwer, B.; Shuman, S.
Molecular and Cellular Biology (2019)

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Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

Journal Article

Minuesa, G.; Albanese, S. K.; Xie, W.; Kazansky, Y.; Worroll, D.; Chow, A.; Schurer, A.; Park, S. M.; Rotsides, C. Z.; Taggart, J.; more...
Nature Communications (2019)

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Activity and structure of Pseudomonas putida MPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster

Journal Article

Ejaz, A.; Goldgur, Y.; Shuman, S.
Journal of Biological Chemistry (2019)

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Structure and two-metal mechanism of fungal tRNA ligase

Journal Article

Banerjee, A.; Ghosh, S.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2019)

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Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates

Journal Article

Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
Journal of Biological Chemistry (2019)

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Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO(4) recognition and ADP-ribosylation

Journal Article

Banerjee, A.; Munir, A.; Abdullahu, L.; Damha, M. J.; Goldgur, Y.; Shuman, S.
Nature Communications (2019)

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Small-molecule targeting of Musashi RNA-binding activity in acute myeloid leukemia

Meeting Abstract

Dinares, G. M.; Albanese, S. K.; Chow, A.; Schurer, A.; Park, S. M.; Rotsides, C. Z.; Taggart, J.; Rizzi, A.; Naden, L. N.; Chou, T.; more...
Blood (2018)

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Distinctive structural basis for DNA recognition by the fission yeast Zn(2)Cys(6) transcription factor Pho7 and its role in phosphate homeostasis

Journal Article

Garg, A.; Goldgur, Y.; Schwer, B.; Shuman, S.
Nucleic Acids Research (2018)

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