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Lee Spraggon

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  1. Journal Article (7)
  2. Meeting Abstract (4)
Groups
  1. Sloan Kettering Institute Postdocs (11)
  2. Human Oncology and Pathogenesis Program (6)
  3. Thoracic Malignancies Disease Management Team (5)
  4. MSK Grad Students (3)
  5. Soft Tissue Sarcoma Disease Management Team (3)
  6. Gerstner Sloan Kettering Graduate School of Biomedical Sciences (2)

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  1. Marc Ladanyi (5)
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  5. Luca Cartegni (3)
  6. Luciano Martelotto (3)

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Years
  1. 2018 (3)
  2. 2017 (2)
  3. 2016 (1)
  4. 2015 (1)
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  6. 2012 (1)
Publications
  1. Cancer Research (2)
  2. Clinical Cancer Research (2)
  3. Proceedings of the National Academy of Sciences of the United States of America (2)
  4. Drug Discovery Today: Therapeutic Strategies (1)
  5. International Journal of Cell Biology (1)
  6. Journal of Cell Biology (1)

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  1. American Association for Cancer Research (4)
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  4. Lee Spraggon and Luca Cartegni (1)
  5. Nature Publishing Group (1)
  6. Rockefeller University Press (1)

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Results (11)

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  • YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics
    Journal Article

    Fan, P. D.; Narzisi, G.; Jayaprakash, A. D.; Venturini, E.; Robine, N.; Smibert, P.; Germer, S.; Yu, H. A.; Jordan, E. J.; Paik, P. K.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2018)

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  • Therapeutic potential of NTRK3 in desmoplastic small round cell tumor
    Meeting Abstract

    Spraggon, L.; Hmeljak, J.; Magnan, H.; Somwar, R.; Asher, M.; Hartono, A. B.; Lee, S. B.; Ladanyi, M.
    Clinical Cancer Research (2018)

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  • Modeling of oncogenic chromosomal translocations of aggressive fusion-positive sarcomas by CRISPR-Cas9 genomic engineering
    Meeting Abstract

    Spraggon, L.; Martelotto, L.; Hmeljak, J.; Hitchman, T.; Wang, J.; Wang, L.; Slotkin, E.; Fan, P. D.; Reis-Filho, J.; Ladanyi, M.
    Clinical Cancer Research (2018)

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  • Generation of conditional oncogenic chromosomal translocations using CRISPR–Cas9 genomic editing and homology-directed repair
    Journal Article

    Spraggon, L.; Martelotto, L. G.; Hmeljak, J.; Hitchman, T. D.; Wang, J.; Wang, L.; Slotkin, E. K.; Fan, P. D.; Reis-Filho, J. S.; Ladanyi, M.
    Journal of Pathology (2017)

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  • Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples
    Journal Article

    Martelotto, L. G.; Baslan, T.; Kendall, J.; Geyer, F. C.; Burke, K. A.; Spraggon, L.; Piscuoglio, S.; Chadalavada, K.; Nanjangud, G.; Ng, C. K. Y.; more...
    Nature Medicine (2017)

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  • Therapeutic targeting of sarcomas driven by EWSR1 fusion oncogenes by modulation of the fusion oncogene pre-mRNA
    Meeting Abstract

    Slotkin, E.; de Stanchina, E.; Cartegni, L.; Ladanyi, M.; Spraggon, L.
    Cancer Research (2016)

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  • In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA
    Journal Article

    La Rocca, G.; Olejniczak, S. H.; González, A. J.; Briskin, D.; Vidigal, J. A.; Spraggon, L.; DeMatteo, R. G.; Radler, M. R.; Lindsten, T.; Ventura, A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2015)

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  • Antisense modulation of RNA processing as a therapeutic approach in cancer therapy
    Journal Article

    Spraggon, L.; Cartegni, L.
    Drug Discovery Today: Therapeutic Strategies (2013)

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  • Reshaping the cancer proteome: Therapeutic targeting of signaling and resistance in cancer by antisense manipulation of RNA processing
    Meeting Abstract

    Cartegni, L.; Spraggon, L.
    Cancer Research (2013)

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  • U1 snrnp-dependent suppression of polyadenylation: Physiological role and therapeutic opportunities in cancer
    Journal Article

    Spraggon, L.; Cartegni, L.
    International Journal of Cell Biology (2013)

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