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Kwangwook Ahn

Formats
  1. Journal Article (9)
  2. Meeting Abstract (1)
Groups
  1. GSK Faculty (10)
  2. Molecular Pharmacology and Chemistry Program Faculty (10)
  3. Population Sciences Research Program (10)
  4. Sloan Kettering Institute Faculty (10)
  5. Sloan Kettering Institute Postdocs (1)
People
  1. Yueming Li (10)
  2. Christina Crump (2)
  3. Christopher Shelton (1)
  4. Deming Chau (1)
  5. Ji Yeun Hur (1)
  6. Lei Zhu (1)

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Years
  1. 2016 (1)
  2. 2013 (2)
  3. 2012 (1)
  4. 2011 (3)
  5. 2010 (2)
  6. 2008 (1)
Publications
  1. Journal of Biological Chemistry (2)
  2. Proceedings of the National Academy of Sciences of the United States of America (2)
  3. ACS Chemical Neuroscience (1)
  4. Abstracts of Papers of the American Chemical Society (1)
  5. Analytical Chemistry (1)
  6. Biochemistry (1)

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Publishers
  1. American Chemical Society (4)
  2. American Society for Biochemistry and Molecular Biology (2)
  3. National Academy of Sciences (2)
  4. Cell Press (1)
  5. Public Library of Science (1)

Results (10)

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  • Imaging and functional analysis of γ-secretase and substrate in a proteolipobead system with an activity-based probe
    Journal Article

    Gilchrist, M. L.; Ahn, K.; Li, Y. M.
    Analytical Chemistry (2016)

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  • Stabilized proteolipobead microenvironments for the functional analysis and drug screening of the cancer and Alzheimer's disease drug target gamma-secretase
    Meeting Abstract

    Gilchrist, L.; Martin, J.; Hur, J. Y.; Li, Y. M.; Ahn, K.; Zhong, L.
    Abstracts of Papers of the American Chemical Society (2013)

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  • γ-secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin
    Journal Article

    Pozdnyakov, N.; Murrey, H. E.; Crump, C. J.; Pettersson, M.; Ballard, T. E.; Am Ende, C. W.; Ahn, K.; Li, Y. M.; Bales, K. R.; Johnson, D. S.
    Journal of Biological Chemistry (2013)

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  • Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies
    Journal Article

    Zhang, X. L.; Hoey, R. J.; Lin, G. Q.; Koide, A.; Leung, B.; Ahn, K.; Dolios, G.; Paduch, M.; Ikeuchi, T.; Wang, R.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2012)

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  • Piperidine acetic acid based γ-secretase modulators directly bind to presenilin-1
    Journal Article

    Crump, C. J.; Fish, B. A.; Castro, S. V.; Chau, D. M.; Gestsik, N.; Ahn, K.; Stiff, C.; Pozdnyakov, N.; Bales, K. R.; Johnson, D. S.; more...
    ACS Chemical Neuroscience (2011)

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  • Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo
    Journal Article

    Li, T.; Li, Y. M.; Ahn, K.; Price, D. L.; Sisodia, S. S.; Wong, P. C.
    PLoS ONE (2011)

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  • Structure of γ-secretase and its trimeric pre-activation intermediate by single-particle electron microscopy
    Journal Article

    Renzi, F.; Zhang, X.; Rice, W. J.; Torres-Arancivia, C.; Gomez-Llorente, Y.; Diaz, R.; Ahn, K.; Yu, C.; Li, Y. M.; Sisodia, S. S.; more...
    Journal of Biological Chemistry (2011)

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  • Modulation of γ-secretase reduces β-amyloid deposition in a transgenic mouse model of Alzheimer's disease
    Journal Article

    Kounnas, M. Z.; Danks, A. M.; Cheng, S.; Tyree, C.; Ackerman, E.; Zhang, X.; Ahn, K.; Nguyen, P.; Comer, D.; Mao, L.; more...
    Neuron (2010)

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  • Activation and intrinsic γ-secretase activity of presenilin 1
    Journal Article

    Ahn, K.; Shelton, C. C.; Tian, Y.; Zhang, X.; Gilchrist, M. L.; Sisodia, S. S.; Li, Y. M.
    Proceedings of the National Academy of Sciences of the United States of America (2010)

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  • Soluble oligomers of the intramembrane serine protease YqgP are catalytically active in the absence of detergents
    Journal Article

    Lei, X.; Ahn, K.; Zhu, L.; Ubarretxena-Belandia, I.; Li, Y. M.
    Biochemistry (2008)

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