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Paul M C Smith

  1. "Molecular Biology Program Faculty"
Formats
  1. Journal Article (20)
Groups
  1. Basic Research Innovation Award (BRIA) (20)
  2. GSK Faculty (20)
  3. Molecular Biology Program Faculty (20)
  4. Sloan Kettering Institute Faculty (20)
  5. MSK Grad Students (2)
  6. Center for Molecular Imaging and Biotechnology (1)

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People
  1. Stewart Shuman (20)
  2. Li-Kai Wang (7)
  3. Ushati Das (6)
  4. Pravin Nair (4)
  5. Agata Jacewicz (2)
  6. Anupam Chakravarty (2)

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Years
  1. 2016 (1)
  2. 2014 (4)
  3. 2013 (2)
  4. 2012 (3)
  5. 2011 (3)
  6. 2010 (3)

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Publications
  1. Nucleic Acids Research (5)
  2. Proceedings of the National Academy of Sciences of the United States of America (3)
  3. RNA (3)
  4. Structure (2)
  5. Acta Crystallographica Section F: Structural Biology Communications (1)
  6. Biochemistry (1)

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Publishers
  1. Oxford University Press (5)
  2. Cell Press (3)
  3. Cold Spring Harbor Laboratory Press (3)
  4. National Academy of Sciences (3)
  5. American Society for Microbiology (2)
  6. American Chemical Society (1)

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Results (20)

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  • Nanomolar inhibitors of Trypanosoma brucei RNA triphosphatase
    Journal Article

    Smith, P.; Ho, C. K.; Takagi, Y.; Djaballah, H.; Shuman, S.
    mBio (2016)

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  • Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28
    Journal Article

    Jacewicz, A.; Schwer, B.; Smith, P.; Shuman, S.
    Nucleic Acids Research (2014)

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  • Structures of bacterial polynucleotide kinase in a Michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide
    Journal Article

    Das, U.; Wang, L. K.; Smith, P.; Munir, A.; Shuman, S.
    Journal of Bacteriology (2014)

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  • Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination
    Journal Article

    Chakravarty, A.; Smith, P.; Jalan, R.; Shuman, S.
    Cell Reports (2014)

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  • Structures of bacterial polynucleotide kinase in a Michaelis complex with GTPMg2+ and 5′-OH oligonucleotide and a product complex with GDPMg2+ and 5′-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition
    Journal Article

    Das, U.; Wang, L. K.; Smith, P.; Jacewicz, A.; Shuman, S.
    Nucleic Acids Research (2014)

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  • Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial Pnkp•Hen1 RNA repair system
    Journal Article

    Das, U.; Wang, L. K.; Smith, P.; Shuman, S.
    Biochemistry (2013)

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  • Structure and mechanism of the 2′,3′ phosphatase component of the bacterial Pnkp-Hen1 RNA repair system
    Journal Article

    Wang, L. K.; Smith, P.; Shuman, S.
    Nucleic Acids Research (2013)

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  • Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system
    Journal Article

    Wang, L. K.; Das, U.; Smith, P.; Shuman, S.
    RNA (2012)

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  • The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family
    Journal Article

    Smith, P.; Wang, L. K.; Nair, P. A.; Shuman, S.
    Proceedings of the National Academy of Sciences of the United States of America (2012)

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  • Structural insights to the metal specificity of an archaeal member of the LigD 3′-phosphoesterase DNA repair enzyme family
    Journal Article

    Das, U.; Smith, P.; Shuman, S.
    Nucleic Acids Research (2012)

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