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Timothy Chan

  1. "Human Oncology and Pathogenesis Program"
Formats
  1. Journal Article (67)
  2. Meeting Abstract (16)
  3. Research Letter (2)
  4. Review (2)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (87)
  2. GSK Faculty (87)
  3. Human Oncology and Pathogenesis Program (87)
  4. Surgery (70)
  5. Department of Medicine (60)
  6. Sloan Kettering Institute Postdocs (53)

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People
  1. Abraham Hakimi (37)
  2. Fengshen Kuo (28)
  3. Luc Morris (27)
  4. Robert Motzer (24)
  5. Martin Voss (23)
  6. Vladimir Makarov (23)

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Years
  1. 2022 (10)
  2. 2021 (9)
  3. 2020 (13)
  4. 2019 (9)
  5. 2018 (6)
  6. 2017 (7)

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Publications
  1. Journal of Clinical Oncology (16)
  2. Clinical Cancer Research (11)
  3. Nature (7)
  4. Nature Communications (5)
  5. Nature Genetics (5)
  6. Proceedings of the National Academy of Sciences of the United States of America (4)

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Publishers
  1. Nature Publishing Group (20)
  2. American Association for Cancer Research (17)
  3. American Society of Clinical Oncology (16)
  4. Oxford University Press (6)
  5. Biomed Central Ltd (4)
  6. Cell Press (4)

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Results (87)

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  • Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
    Journal Article

    Alatise, O. I.; Knapp, G. C.; Sharma, A.; Chatila, W. K.; Arowolo, O. A.; Olasehinde, O.; Famurewa, O. C.; Omisore, A. D.; Komolafe, A. O.; Olaofe, O. O.; more...
    Nature Communications (2021)

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  • Prevalence and landscape of actionable genomic alterations in renal cell carcinoma
    Journal Article

    Attalla, K.; DiNatale, R. G.; Rappold, P. M.; Fong, C. J.; Sanchez-Vega, F.; Silagy, A. W.; Weng, S.; Coleman, J.; Lee, C. H.; Carlo, M. I.; more...
    Clinical Cancer Research (2021)

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  • High response rate and durability driven by HLA genetic diversity in patients with kidney cancer treated with lenvatinib and pembrolizumab
    Journal Article

    Lee, C. H.; DiNatale, R. G.; Chowell, D.; Krishna, C.; Makarov, V.; Valero, C.; Vuong, L.; Lee, M.; Weiss, K.; Hoen, D.; more...
    Molecular Cancer Research (2021)

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  • Response rates to anti-PD-1 immunotherapy in microsatellite-stable solid tumors with 10 or more mutations per megabase
    Journal Article

    Valero, C.; Lee, M.; Hoen, D.; Zehir, A.; Berger, M. F.; Seshan, V. E.; Chan, T. A.; Morris, L. G. T.
    JAMA Oncology (2021)

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  • Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy
    Journal Article

    Krishna, C.; DiNatale, R. G.; Kuo, F.; Srivastava, R. M.; Vuong, L.; Chowell, D.; Gupta, S.; Vanderbilt, C.; Purohit, T. A.; Liu, M.; more...
    Cancer Cell (2021)

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  • Therapy-relevant gene signatures in the high risk localized renal cell carcinoma setting: Transcriptomic data from patients receiving placebo on a randomized phase III trial (PROTECT)
    Meeting Abstract

    Rappold, P. M.; Silagy, A. W.; Kuo, F.; Marker, M.; Reising, A.; Millholland, J.; Russo, P.; Coleman, J.; Voss, M. H.; Chan, T. A.; more...
    Journal of Clinical Oncology (2021)

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  • Putative drivers of aggressiveness in TCEB1-mutant renal cell carcinoma: An emerging entity with variable clinical course
    Journal Article

    DiNatale, R. G.; Gorelick, A. N.; Makarov, V.; Blum, K. A.; Silagy, A. W.; Freeman, B.; Chowell, D.; Marcon, J.; Mano, R.; Sanchez, A.; more...
    European Urology Focus (2021)

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  • Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors
    Journal Article

    Valero, C.; Lee, M.; Hoen, D.; Weiss, K.; Kelly, D. W.; Adusumilli, P. S.; Paik, P. K.; Plitas, G.; Ladanyi, M.; Postow, M. A.; more...
    Nature Communications (2021)

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  • The association between tumor mutational burden and prognosis is dependent on treatment context
    Research Letter

    Valero, C.; Lee, M.; Hoen, D.; Wang, J.; Nadeem, Z.; Patel, N.; Postow, M. A.; Shoushtari, A. N.; Plitas, G.; Balachandran, V. P.; more...
    Nature Genetics (2021)

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  • Sarcomatoid renal cell carcinoma: Biology, natural history and management
    Review

    Blum, K. A.; Gupta, S.; Tickoo, S. K.; Chan, T. A.; Russo, P.; Motzer, R. J.; Karam, J. A.; Hakimi, A. A.
    Nature Reviews Urology (2020)

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