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Mihaela Carmen Sandu

Formats
  1. Journal Article (19)
Groups
  1. Sloan Kettering Institute Postdocs (19)
  2. Basic Research Innovation Award (BRIA) (18)
  3. GSK Faculty (18)
  4. Molecular Biology Program Faculty (18)
  5. Sloan Kettering Institute Faculty (18)
  6. Department of Medicine (4)

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People
  1. Stewart Shuman (18)
  2. Yehuda Goldgur (5)
  3. Michael Glickman (4)
  4. Krishna Sinha (2)
  5. Richa Gupta (2)
  6. Dinshaw Patel (1)

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Years
  1. 2021 (2)
  2. 2020 (1)
  3. 2019 (2)
  4. 2017 (2)
  5. 2016 (1)
  6. 2015 (2)

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Publications
  1. Biochemistry (4)
  2. Nucleic Acids Research (4)
  3. Proceedings of the National Academy of Sciences of the United States of America (4)
  4. Journal of Biological Chemistry (3)
  5. RNA (2)
  6. Genes and Development (1)

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Publishers
  1. American Chemical Society (4)
  2. National Academy of Sciences (4)
  3. Oxford University Press (4)
  4. American Society for Biochemistry and Molecular Biology (3)
  5. Cold Spring Harbor Laboratory Press (3)
  6. American Society for Microbiology (1)

Results (19)

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  • Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase
    Journal Article

    Unciuleac, M. C.; Ghosh, S.; de la Cruz, M. J.; Goldgur, Y.; Shuman, S.
    RNA (2021)

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  • Clutch mechanism of chemomechanical coupling in a DNA resecting motor nuclease
    Journal Article

    Unciuleac, M. C.; Meir, A.; Xue, C.; Warren, G. M.; Greene, E. C.; Shuman, S.
    Proceedings of the National Academy of Sciences of the United States of America (2021)

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  • Caveat mutator: Alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation
    Journal Article

    Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
    Nucleic Acids Research (2020)

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  • Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection
    Journal Article

    Jia, N.; Unciuleac, M. C.; Xue, C.; Greene, E. C.; Patel, D. J.; Shuman, S.
    Proceedings of the National Academy of Sciences of the United States of America (2019)

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  • Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates
    Journal Article

    Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
    Journal of Biological Chemistry (2019)

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  • Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases
    Journal Article

    Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
    Proceedings of the National Academy of Sciences of the United States of America (2017)

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  • Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases
    Journal Article

    Gupta, R.; Unciuleac, M. C.; Shuman, S.; Glickman, M. S.
    Nucleic Acids Research (2017)

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  • Crystal structure and biochemical characterization of a Mycobacterium smegmatis AAA-type nucleoside triphosphatase phosphohydrolase (Msm0858)
    Journal Article

    Unciuleac, M. C.; Smith, P. C.; Shuman, S.
    Journal of Bacteriology (2016)

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  • Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase
    Journal Article

    Unciuleac, M. C.; Goldgur, Y.; Shuman, S.
    Proceedings of the National Academy of Sciences of the United States of America (2015)

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  • Characterization of a novel eukaryal nick-sealing RNA ligase from Naegleria gruberi
    Journal Article

    Unciuleac, M. C.; Shuman, S.
    RNA (2015)

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