Synapse - Shane Curran

Results (10)

Primary T cells from cutaneous T-cell lymphoma skin explants display an exhausted immune checkpoint profile

Journal Article

Querfeld, C.; Leung, S.; Myskowski, P. L.; Curran, S. A.; Goldman, D. A.; Heller, G.; Wu, X.; Kil, S. H.; Sharma, S.; Finn, K. J.; more...
Cancer Immunology Research (2018)

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Human dendritic cells mitigate NK-cell dysfunction mediated by nonselective JAK1/2 blockade

Journal Article

Curran, S. A.; Shyer, J. A.; St Angelo, E. T.; Talbot, L. R.; Sharma, S.; Chung, D. J.; Heller, G.; Hsu, K. C.; Betts, B. C.; Young, J. W.
Cancer Immunology Research (2017)

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T-cell exhaustion in multiple myeloma relapse after autotransplant: Optimal timing of immunotherapy

Journal Article

Chung, D. J.; Pronschinske, K. B.; Shyer, J. A.; Sharma, S.; Leung, S.; Curran, S. A.; Lesokhin, A. M.; Devlin, S. M.; Giralt, S. A.; Young, J. W.
Cancer Immunology Research (2016)

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T cell exhaustion/senescence in relapsed multiple myeloma after autologous stem cell transplantation

Meeting Abstract

Chung, D. J.; Pronschinske, K. B.; Shyer, J. A.; Sharma, S.; Leung, S.; Curran, S. A.; Lesokhin, A. M.; Devlin, S.; Giralt, S. A.; Young, J. W.
Blood (2015)

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T cells in CTCL have an exhausted phenotype while cutaneous dendritic cells display a normally activated mature phenotype

Meeting Abstract

Querfeld, C.; Curran, S. A.; Leung, S.; Myskowski, P. L.; Horwitz, S. M.; Halpern, A. C.; Young, J. W.
Blood (2014)

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Phenotypic and functional activation of hyporesponsive KIR(neg)NKG2A(neg) human NK-cell precursors requires IL12p70 provided by poly(I:C)-matured monocyte-derived dendritic cells

Journal Article

Curran, S. A.; Romano, E.; Kennedy, M. G.; Hsu, K. C.; Young, J. W.
Cancer Immunology Research (2014)

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Targeted Janus kinase-2 inhibition overcomes limitations of IL6-receptor-alpha blockade in controlling human DC-stimulated alloreactivity

Meeting Abstract

Betts, B. C.; Abdel-Wahab, O.; Curran, S. A.; St Angelo, E. T.; Koppikar, P.; Kennedy, M.; Heller, G.; Levine, R. L.; Young, J. W.
Biology of Blood and Marrow Transplantation (2012)

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Janus kinase-2 inhibition induces durable tolerance to alloantigen by dendritic cell-stimulated human T cells, yet preserves immunity to recall antigen

Meeting Abstract

Betts, B. C.; Abdel-Wahab, O.; Curran, S. A.; St Angelo, E. T.; Koppikar, P.; Heller, G.; Levine, R. L.; Young, J. W.
Blood (2011)

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Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen