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Jorge Mansilla-Soto

Formats
  1. Journal Article (24)
  2. Meeting Abstract (23)
  3. Review (1)
Groups
  1. Sloan Kettering Institute Postdocs (48)
  2. Center for Hematologic Malignancies (42)
  3. Department of Medicine (42)
  4. GSK Faculty (42)
  5. Hematologic Malignancies Research (42)
  6. Hematologic Malignancies, Division of (42)

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People
  1. Michel Sadelain (42)
  2. Isabelle Riviere (18)
  3. Justin Eyquem (16)
  4. Mohamad Hamieh (12)
  5. Xiuyan Wang (10)
  6. Judith Feucht (9)

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Years
  1. 2025 (2)
  2. 2023 (9)
  3. 2022 (5)
  4. 2021 (3)
  5. 2020 (3)
  6. 2019 (4)

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Publications
  1. Molecular Therapy (11)
  2. Blood (9)
  3. Nature (5)
  4. Cancer Cell (2)
  5. Nature Medicine (2)
  6. British Journal of Haematology (1)

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Publishers
  1. Nature Publishing Group (20)
  2. American Society of Hematology (9)
  3. Cell Press (5)
  4. American Association for Cancer Research (3)
  5. Elsevier Inc. (2)
  6. Public Library of Science (2)

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Results (48)

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  • HIV immune evasin Nef enhances allogeneic CAR T cell potency
    Journal Article

    Perica, K.; Kotchetkov, I. S.; Mansilla-Soto, J.; Ehrich, F.; Herrera, K.; Shi, Y.; Dobrin, A.; Gönen, M.; Sadelain, M.
    Nature (2025)

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  • Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
    Journal Article

    Sætersmoen, M.; Kotchetkov, I. S.; Torralba-Raga, L.; Mansilla-Soto, J.; Sohlberg, E.; Krokeide, S. Z.; Hammer, Q.; Sadelain, M.; Malmberg, K. J.
    Med (2025)

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  • A phase I study of CD19-targeted 19(T2)28z1xx CAR T cells in adult patients with relapsed or refractory diffuse large B-cell lymphoma
    Meeting Abstract

    Park, J. H.; Palomba, M. L.; Devlin, S. M.; Valtis, Y. K.; Sikder, D. S.; Senechal, B.; Wang, X.; Cathcart, E.; Liotta, K.; Yu, A.; more...
    Blood (2023)

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  • Cooperative CAR targeting to selectively eliminate AML and minimize escape
    Journal Article

    Haubner, S.; Mansilla-Soto, J.; Nataraj, S.; Kogel, F.; Chang, Q.; de Stanchina, E.; Lopez, M.; Ng, M. R.; Fraser, K.; Subklewe, M.; more...
    Cancer Cell (2023)

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  • Allogeneic CAR T cells with regulated NEF expression display immune evasion and optimized signaling
    Meeting Abstract

    Perica, K.; Mansilla-Soto, J.; Kotchetkov, I.; Sadelain, M.
    Molecular Therapy (2023)

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  • Characterizing the relationship between cellular kinetics and response to support dosing recommendations for Cd19-targeted 19(T2)28z1xx cell therapy
    Meeting Abstract

    Li, J.; Singh, R.; Dey, A.; Sellner, L.; Liu, R.; Dash, A.; Park, J.; Palomba, M.; Mansilla-Soto, J.; Senechal, B.; more...
    Clinical Pharmacology & Therapeutics (2023)

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  • Novel extragenic genomic safe harbors for precise therapeutic T-cell engineering
    Journal Article

    Odak, A.; Yuan, H.; Feucht, J.; Cantu, V. A.; Mansilla-Soto, J.; Kogel, F.; Eyquem, J.; Everett, J.; Bushman, F. D.; Leslie, C. S.; more...
    Blood (2023)

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  • Programming CAR T cell tumor recognition: Tuned antigen sensing and logic gating
    Review

    Hamieh, M.; Mansilla-Soto, J.; Rivière, I.; Sadelain, M.
    Cancer Discovery (2023)

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  • TET2 guards against unchecked BATF3-induced CAR T cell expansion
    Journal Article

    Jain, N.; Zhao, Z.; Feucht, J.; Koche, R.; Iyer, A.; Dobrin, A.; Mansilla-Soto, J.; Yang, J.; Zhan, Y.; Lopez, M.; more...
    Nature (2023)

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  • CD19 CAR antigen engagement mechanisms and affinity tuning
    Journal Article

    He, C.; Mansilla-Soto, J.; Khanra, N.; Hamieh, M.; Bustos, V.; Paquette, A. J.; Garcia Angus, A.; Shore, D. M.; Rice, W. J.; Khelashvili, G.; more...
    Science Immunology (2023)

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