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Poulikos I Poulikakos

Formats
  1. Meeting Abstract (14)
  2. Journal Article (9)
Groups
  1. Department of Medicine (22)
  2. GSK Faculty (22)
  3. Solid Tumor Oncology Division (22)
  4. Breast Medicine Service (21)
  5. Molecular Pharmacology and Chemistry Program Faculty (21)
  6. Sloan Kettering Institute Faculty (21)

More Groups

People
  1. Neal Rosen (21)
  2. David Solit (10)
  3. Eric Joseph (10)
  4. Christine Pratilas (8)
  5. Madhavi Tadi (8)
  6. Sarat Chandarlapaty (7)

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Years
  1. 2014 (1)
  2. 2013 (3)
  3. 2012 (6)
  4. 2011 (6)
  5. 2010 (3)
  6. 2009 (1)

More Years

Publications
  1. Cancer Research (13)
  2. Cancer Cell (2)
  3. Nature (2)
  4. Cancer Discovery (1)
  5. European Journal of Cancer (1)
  6. Molecular Cancer Research (1)

More Publications

Publishers
  1. American Association for Cancer Research (15)
  2. Nature Publishing Group (3)
  3. Cell Press (2)
  4. American Association for the Advancement of Science (1)
  5. Elsevier Inc. (1)
  6. National Academy of Sciences (1)

Results (23)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • Oncogenic RAF mutants that signal as functional dimers are resistant to current RAF inhibitors but sensitive to a novel inhibitor of RAF dimer kinase activity
    Meeting Abstract

    Yao, Z.; Torres, N. M.; Wei, M.; Hanrahan, A.; Abdel-Wahab, O.; Solit, D.; Luo, L.; Poulikakos, P.; Rosen, N.
    Molecular Cancer Research (2014)

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  • Rapid induction of apoptosis by PI3K inhibitors is dependent upon their transient inhibition of RAS signaling
    Meeting Abstract

    Will, M.; Toy, W.; Yao, Z.; Poulikakos, P.; Rodrik-Outmezguine, V. ; Schneider, C.; Paul, J.; Baselga, J.; Liu, N.; Rosen, N.; more...
    Cancer Research (2013)

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  • Feedback dependent suppression of mitogenic signaling and its effect on RAF inhibition in BRAFV600E melanomas
    Meeting Abstract

    Lito, P.; Pratilas, C.; Joseph, E.; Tadi, M.; Halilovic, E.; Zubrowski, M.; Huang, A.; de Stanchina, E.; Chandarlapaty, S.; Poulikakos, P.; more...
    Cancer Research (2013)

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  • Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of raf activity
    Journal Article

    Ishii, N.; Harada, N.; Joseph, E. W.; Ohara, K.; Miura, T.; Sakamoto, H.; Matsuda, Y.; Tomii, Y.; Tachibana-Kondo, Y.; Iikura, H.; more...
    Cancer Research (2013)

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  • Relief of feedback inhibition of RTK and RAS signaling in V600E BRAF melanomas exposed to RAF inhibitors buffers their effects on signaling
    Meeting Abstract

    Pratilas, C. A.; Joseph, E. W.; Tadi, M.; Poulikakos, P. I.; Gabay, M.; Lito, P.; Wong, W.; DeStanchina, E.; Chandarlapaty, S.; Rosen, N.
    Cancer Research (2012)

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  • RAS-independent dimerization of BRAF(V600E) splicing variants promotes resistance to RAF inhibitors
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Kong, X.; Ng, C.; Moriceau, G.; Shi, H.; Atefi, M.; Titz, B.; Gabay, M. T.; more...
    Cancer Research (2012)

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  • mTOR kinase inhibition relieves feedback suppression of receptor tyrosine kinase leading to a biphasic regulation of AKT signaling in breast cancer cells
    Meeting Abstract

    Rodrik-Outmezguine, V. S.; Chandarlapaty, S.; Pagano, N. C.; Poulikakos, P. I.; Scaltriti, M.; Baselga, J.; Guichard, S.; Rosen, N.
    Cancer Research (2012)

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  • Reactivation of oncogenic signaling through mTOR inhibitors-induced feedback adaptations
    Meeting Abstract

    Rodrik-Outmezguine, V.; Chandarlapaty, S.; Poulikakos, P.; Scaltriti, M.; Baselga, J.; Rosen, N.
    Cancer Research (2012)

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  • Resistance to RAF inhibitors due to RAS-independent dimerization of BRAF(V600E) splicing variants
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Janakiraman, M.; Gabay, M. T.; Dahlman, K. B.; Sosman, J. A.; Ribas, A.; Lo, R. S.; Rosen, N.; Solit, D. B.
    European Journal of Cancer (2012)

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  • Relief of profound feedback inhibition of mitogenic signaling by RAF inhibitors attenuates their activity in BRAFV600E melanomas
    Journal Article

    Lito, P.; Pratilas, C. A.; Joseph, E. W.; Tadi, M.; Halilovic, E.; Zubrowski, M.; Huang, A.; Wong, W. L.; Callahan, M. K.; Merghoub, T.; more...
    Cancer Cell (2012)

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