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Guenther Koehne

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Human lymphocytes sensitized to HLA A0201 and HLA A2402 binding WT-1 peptides loaded on autologous cytokine activated monocytes or EBV transformed B cells yield HLA restricted WT-1 peptide specific cytotoxic T cells that lyse primary WT-1+leukemic cells in vitro and, in vivo, home to and induced regression of WT-1+leukemic xenografts bearing the restricting HLA alleles

Meeting Abstract

Doubrovina, E.; Guerrero, J.; Lee, S. Y.; Koehne, G.; Doubrovin, M.; Diaz-Barrientos, T.; O'Reilly, R. J.
Blood (2002)

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Down-regulation of effector function of EBV peptide-specific T cells isolated with MHC tetramers

Meeting Abstract

Koehne, G.; Leiner, I.; Vyas, Y.; Williams, R. Y.; Pamer, E. G.; O'Reilly, R. J.
Blood (2002)

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Quantitation, selection, and functional characterization of Epstein-Barr virus-specific and alloreactive T cells detected by intracellular interferon-γ production and growth of cytotoxic precursors

Journal Article

Koehne, G.; Smith, K. M.; Ferguson, T. L.; Williams, R. Y.; Heller, G.; Pamer, E. G.; Dupont, B.; O'Reilly, R. J.
Blood (2002)

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Selection of viable Interferon-gamma secreting T lymphocytes for adoptive immunotherapy of EBV-lymphoproliferative disorders (EBV-LPD)

Meeting Abstract

Koehne, G.; Smith, K. M.; Williams, R. Y.; Ferguson, T. L.; Dupont, B.; O'Reilly, R. J.
Blood (2001)

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Noninvasive imaging of human radiolabeled antigen-specific donor T lymphocytes after adoptive immunotherapy in SCID mice

Meeting Abstract

Koehne, G.; Zanzonico, P.; Gallardo, H. F.; May, C.; Balatoni, J.; Riviere, I.; O'Reilly, R. J.; Sadelain, M.; Larson, S. M.
Blood (2000)

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Controlled graft-versus-leukemia reaction after adoptive transfer of HSV-TK modified allogeneic donor T lymphocytes sensitized with B7.1 transduced ALL cells

Meeting Abstract

Koehne, G.; Gallardo, H. F.; Latouche, J. B.; May, C.; Steinherz, P.; Heller, G.; Sadelain, M.; O'Reilly, R. J.
Blood (2000)

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PNH cells are as sensitive to T-cell-mediated lysis as their normal counterparts: Implications for the pathogenesis of paroxysmal nocturnal haemoglobinuria

Journal Article

Karadimitris, A.; Notaro, R.; Koehne, G.; Roberts, I. A. G.; Luzzatto, L.
British Journal of Haematology (2000)

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Rapid selection of antigen-specific T lymphocytes by retroviral transduction

Journal Article

Koehne, G.; Gallardo, H. F.; Sadelain, M.; O'Reilly, R. J.
Blood (2000)

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Selective infection of dividing lymphocytes by retroviral vectors encoding a mutant NGFR and herpes simplex virus-thymidine kinase gene permits preferential enrichment of virus-specific T cells for adoptive cell therapy

Meeting Abstract

Koehne, G.; Gallardo, H. F.; Sadelain, M.; O'Reilly, R. J.
Bone Marrow Transplantation (1999)

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Quantitative analysis of EBV-specific T cells in retrovirally transduced donor leukocytes after stimulation with mitogens or autologous EBV-BLCL

Meeting Abstract

Koehne, G.; Gallardo, H. F.; Sadelain, M.; O'Reilly, R. J.
Blood (1999)

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