Synapse - David Hyman

Results (81)

Next-generation sequencing of matched normal blood identifies clonal hematopoiesis in a significant subset of solid tumor patients without hematologic malignancies

Meeting Abstract

Coombs, C. C.; Zehir, A.; Devlin, S.; Middha, S.; Cheng, D.; Kishtagari, A.; Hyman, D. M.; Solit, D.; Robson, M.; Baselga, J.; more...
Blood (2015)

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Precision medicine at Memorial Sloan Kettering Cancer Center: Clinical next-generation sequencing enabling next-generation targeted therapy trials

Journal Article

Hyman, D. M.; Solit, D. B.; Arcila, M. E.; Cheng, D. T.; Sabbatini, P.; Baselga, J.; Berger, M. F.; Ladanyi, M.
Drug Discovery Today (2015)

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Prospective identification of potentially actionable molecular alterations in cancers of unknown primary

Meeting Abstract

Varghese, A. M.; Hyman, D. M.; Zehir, A.; Vakiani, E.; Klimstra, D. S.; Ladanyi, M.; Berger, M. F.; Solit, D. B.; Saltz, L.
Journal of Clinical Oncology (2015)

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Tumor relevant germline findings in targeted tumor sequencing using matched normal DNA of 1,570 unselected cases

Meeting Abstract

Schrader, K. A.; Cheng, D. T.; Vijai, J.; Prasad, M.; Walsh, M.; Zehir, A.; Thomas, T.; Benayed, R.; Stadler, Z. K.; Ashraf, A.; more...
Journal of Clinical Oncology (2015)

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The clinical utility of ERBB2 amplification detection in breast carcinoma using a 341 gene hybrid capture-based next generation sequencing (NGS) assay: Comparison with standard immunohistochemistry (IHC) and Fluorescence In Situ Hybridization (FISH) assays

Meeting Abstract

Ross, D. S.; Zehir, A.; Cheng, D. T.; Nafa, K.; Jour, G.; Razavi, P.; Hyman, D. M.; Baselga, J.; Berger, M. F.; Ladanyi, M.; more...
Journal of Clinical Oncology (2015)

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Is next generation sequencing (NGS) ready for routine clinical practice in gliomas? Results of a prospective study utilizing the MSK-IMPACT assay

Meeting Abstract

Omuro, A. M. P.; Zehir, A.; Cheng, D. T.; Berger, M. F.; Hyman, D. M.; Solit, D. B.; Baselga, J.; Ladanyi, M.; Arcila, M. E.; Hameed, M.; more...
Journal of Clinical Oncology (2015)

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Identification of novel and potentially targetable receptor tyrosine kinase alterations in colorectal carcinoma using a 341 gene hybrid capture-based next-generation sequencing assay

Meeting Abstract

Hechtman, J. F.; Arcila, M. E.; Cheng, D. T.; Solit, D. B.; Yaeger, R. D.; Hyman, D. M.; Berger, M. F.; Shia, J.; Vakiani, E.; Zehir, A.; more...
Journal of Clinical Oncology (2015)

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Comprehensive assessment of targetable alterations in lung adenocarcinoma samples with limited material using MSK-IMPACT, a clinical, hybrid capture-based, next-generation sequencing (NGS) assay

Meeting Abstract

Arcila, M. E.; Yu, H. A.; Drilon, A. E.; Riely, G. J.; Zehir, A.; Sadowska, J.; Hyman, D. M.; Kris, M. G.; Berger, M. F.; Ladanyi, M.
Journal of Clinical Oncology (2015)

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Comparison of genetic alterations from the bladder cancer genome atlas (TCGA) and a prospective set of high-grade urothelial carcinoma tumors using a CLIA laboratory next generation sequencing assay

Meeting Abstract

Iyer, G.; Bagrodia, A.; Cha, E. K.; Boyd, M. E.; Zehir, A.; Cheng, D. T.; Hyman, D. M.; Bambury, R. M.; Arcila, M. E.; Ladanyi, M.; more...
Journal of Clinical Oncology (2015)

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Comprehensive assessment of RAS/RAF mutation status and identification of alternative targetable driver alterations in RAS/RAF wild type colorectal carcinoma using a hybrid capture-based next-generation sequencing assay

Meeting Abstract

Hechtman, J.; Zehir, A.; Cheng, D.; Shia, J. R.; Solit, D.; Yaeger, R.; Hyman, D.; Arcila, M.; Berger, M.; Ladanyi, M.; more...
Modern Pathology (2015)

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