Synapse - Geoffrey Oxnard

Results (14)

Screening for germline EGFR T790M mutations through lung cancer genotyping

Journal Article

Oxnard, G. R.; Miller, V. A.; Robson, M. E.; Azzoli, C. G.; Pao, W.; Ladanyi, M.; Arcila, M. E.
Journal of Thoracic Oncology (2012)

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Resolving the controversy on EGFR/KRAS mutations in pulmonary squamous cell carcinoma via comprehensive pathologic assessment incorporating immunohistochemistry

Meeting Abstract

Rekhtman, N.; Paik, P. K.; Arcila, M. E.; Tafe, L. J.; Oxnard, G. R.; Moreira, A. L.; William, T. D.; Zakowski, M. F.; Mark, K. G.; Ladanyi, M.
Modern Pathology (2012)

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Resolving the controversy on EGFR/KRAS mutations in pulmonary squamous cell carcinoma via comprehensive pathologic assessment incorporating immunohistochemistry

Meeting Abstract

Rekhtman, N.; Paik, P. K.; Arcila, M. E.; Tafe, L. J.; Oxnard, G. R.; Moreira, A. L.; William, T. D.; Zakowski, M. F.; Mark, K. G.; Ladanyi, M.
Laboratory Investigation (2012)

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Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: Lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations

Journal Article

Rekhtman, N.; Paik, P. K.; Arcila, M. E.; Tafe, L. J.; Oxnard, G. R.; Moreira, A. L.; Travis, W. D.; Zakowski, M. F.; Kris, M. G.; Ladanyi, M.
Clinical Cancer Research (2012)

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Maintained sensitivity to EGFR tyrosine kinase inhibitors (TKIs) in EGFR-mutant lung cancers that recur after adjuvant TKI

Meeting Abstract

Oxnard, G. R.; Janjigian, Y. Y.; Arcila, M. E.; Kris, M. G.; Ladanyi, M.; Azzoli, C. G.; Miller, V. A.
Journal of Clinical Oncology (2011)

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Maintained sensitivity to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer recurring after adjuvant erlotinib or gefitinib

Journal Article

Oxnard, G. R.; Janjigian, Y. Y.; Arcila, M. E.; Sima, C. S.; Kass, S. L.; Riely, G. J.; Pao, W.; Kris, M. G.; Ladanyi, M.; Azzoli, C. G.; more...
Clinical Cancer Research (2011)

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Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling

Journal Article

Chmielecki, J.; Foo, J.; Oxnard, G. R.; Hutchinson, K.; Ohashi, K.; Somwar, R.; Wang, L.; Amato, K. R.; Arcila, M.; Sos, M. L.; more...
Science Translational Medicine (2011)

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Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation

Journal Article

Oxnard, G. R.; Arcila, M. E.; Sima, C. S.; Riely, G. J.; Chmielecki, J.; Kris, M. G.; Pao, W.; Ladanyi, M.; Miller, V. A.
Clinical Cancer Research (2011)

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Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay