Research Focus

Former Employee. Chemical Biology Program; Research Fellow

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1. Total synthesis of TMC-95A and -B via a new reaction leading to Z-enamides. Some preliminary findings as to SAR

   Journal Article

   Lin, S.; Yang, Z. Q.; Kwok, B. H. B.; Koldobskiy, M.; Crews, C. M.; Danishefsky, S. J.
   Journal of the American Chemical Society (2004)

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2. New efficient synthesis of resorcinylic macrolides via ynolides: Establishment of cycloproparadicicol as synthetically feasible preclinical anticancer agent based on Hsp90 as the target

   Journal Article

   Yang, Z. Q.; Geng, X.; Solit, D.; Pratilas, C. A.; Rosen, N.; Danishefsky, S. J.
   Journal of the American Chemical Society (2004)

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3. Synthetic development of radicicol and cycloproparadicicol: Highly promising anticancer agents targeting hsp90

   Journal Article

   Geng, X.; Yang, Z. Q.; Danishefsky, S. J.
   Synlett (2004)

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