Synapse - Marc Ladanyi

Results (47)

Methylation analysis reveals epigenetic congruence between bone sarcomas with H3-3A mutations and malignant giant cell tumors of bone

Journal Article

Saoud, C.; Benhamida, J.; Borsu, L.; Villafania, L.; Linos, K.; Brannon, A. R.; Sinchun, H.; Morris, C.; Vaynrub, M.; Bartelstein, M.; more...
Modern Pathology (2025)

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Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy

Journal Article

Kazansky, Y.; Cameron, D.; Mueller, H. S.; Demarest, P.; Zaffaroni, N.; Arrighetti, N.; Zuco, V.; Kuwahara, Y.; Somwar, R.; Ladanyi, M.; more...
Cancer Discovery (2024)

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Distinct IDH1/2-associated methylation profile and enrichment of TP53 and TERT mutations distinguish dedifferentiated chondrosarcoma from conventional chondrosarcoma

Journal Article

Dermawan, J. K. T.; Nafa, K.; Mohanty, A.; Xu, Y.; Rijo, I.; Casanova, J.; Villafania, L.; Benhamida, J.; Kelly, C. M.; Tap, W. D.; more...
Cancer Research Communications (2023)

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Undifferentiated and dedifferentiated metastatic melanomas masquerading as soft tissue sarcomas: Mutational signature analysis and immunotherapy response

Journal Article

Kasago, I. S.; Chatila, W. K.; Lezcano, C. M.; Febres-Aldana, C. A.; Schultz, N.; Vanderbilt, C.; Dogan, S.; Bartlett, E. K.; D'Angelo, S. P.; Tap, W. D.; more...
Modern Pathology (2023)

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Prospective clinical genomic profiling of Ewing sarcoma: ERF and FGFR1 mutations as recurrent secondary alterations of potential biologic and therapeutic relevance

Journal Article

Ogura, K.; Elkrief, A.; Bowman, A. S.; Koche, R. P.; de Stanchina, E.; Benayed, R.; Mauguen, A.; Mattar, M. S.; Khodos, I.; Meyers, P. A.; more...
JCO Precision Oncology (2022)

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Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets

Meeting Abstract

Nacev, B. A.; Sanchez-Vega, F.; Smith, S.; Antonescu, C.; Rosenbaum, E.; Shi, H.; Tang, C.; Socci, N.; Rana, S.; Gularte-Merida, R.; more...
Clinical Cancer Research (2022)

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Distinct IDH1/2-associated methylation profile and enrichment of TP53 and TERT mutations distinguish dedifferentiated chondrosarcoma from conventional chondrosarcoma on integrated genomic and epigenomic profiling

Meeting Abstract

Dermawan, J.; Nafa, K.; Mohanty, A.; Xu, Y.; Rijo, I.; Villafania, L.; Benhamida, J.; Kelly, C.; Tap, W.; Boland, P.; more...
Journal of Molecular Diagnostics (2022)

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Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets

Journal Article

Nacev, B. A.; Sanchez-Vega, F.; Smith, S. A.; Antonescu, C. R.; Rosenbaum, E.; Shi, H.; Tang, C.; Socci, N. D.; Rana, S.; Zehir, A.; more...
Nature Communications (2022)

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma

Journal Article

Gounder, M. M.; Agaram, N. P.; Trabucco, S. E.; Robinson, V.; Ferraro, R. A.; Millis, S. Z.; Krishnan, A.; Lee, J.; Attia, S.; Abida, W.; more...
Nature Communications (2022)

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Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Journal Article

Nguyen, B.; Fong, C.; Luthra, A.; Smith, S. A.; DiNatale, R. G.; Nandakumar, S.; Walch, H.; Chatila, W. K.; Madupuri, R.; Kundra, R.; more...
Cell (2022)

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