Synapse - Stewart Shuman

Results (546)

Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial Pnkp•Hen1 RNA repair system

Journal Article

Das, U.; Wang, L. K.; Smith, P.; Shuman, S.
Biochemistry (2013)

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Structure and mechanism of the 2′,3′ phosphatase component of the bacterial Pnkp-Hen1 RNA repair system

Journal Article

Wang, L. K.; Smith, P.; Shuman, S.
Nucleic Acids Research (2013)

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Eradication of melanoma by intratumoral injection of attenuated vaccinia virus requires CD8+ T cells and combination of anti-CTLA-4 blockade and virotherapy enhances therapeutic efficacy in advanced melanoma

Meeting Abstract

Wu, X.; Dai, P.; Wang, W.; Avogadri, F.; Cao, H.; Parikh, T.; Jiang, X.; Halpern, A. C.; Houghton, A. N.; Shuman, S.; more...
Journal of Investigative Dermatology (2013)

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STING (stimulator of interferon genes) is required for the induction of autophagy in conventional dendritic cells and macrophages in response to infection by modified vaccinia virus Ankara

Meeting Abstract

Wang, W.; Parikh, T.; Dai, P.; Gammoh, N.; Ganley, I.; Kim, S.; Vance, R.; Virgin, H. W.; Overholtzer, M.; Shuman, S.; more...
Journal of Investigative Dermatology (2013)

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Modified vaccinia virus Ankara induces type I IFN induction in conventional dendritic cells through a STING-mediated cytosolic DNA sensing pathway that requires IRF3, IRF7 and IFNAR1

Meeting Abstract

Dai, P.; Wang, W.; Cao, H.; Avogadri, F.; Vance, R.; Merghoub, T.; Shuman, S.; Deng, L.
Journal of Investigative Dermatology (2013)

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Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase

Journal Article

Unciuleac, M. C.; Shuman, S.
Biochemistry (2013)

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A kinetic framework for tRNA ligase and enforcement of a 2'-phosphate requirement for ligation highlights the design logic of an RNA repair machine

Journal Article

Remus, B. S.; Shuman, S.
RNA (2013)

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Mycobacterium smegmatis Lhr is a DNA-dependent ATPase and a 3′-to-5′ DNA translocase and helicase that prefers to unwind 3′-tailed RNA:DNA hybrids