Synapse - Stewart Shuman

Results (39)

Two-step mechanism and step-arrest mutants of Runella slithyformis NAD(+)-dependent tRNA 2′-phosphotransferase Tpt1

Journal Article

Munir, A.; Abdullahu, L.; Damha, M. J.; Shuman, S.
RNA (2018)

Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities

Journal Article

Uson, M. L.; Carl, A.; Goldgur, Y.; Shuman, S.
Nucleic Acids Research (2018)

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Structure of mycobacterial 3'-to-5' RNA: DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases

Journal Article

Ejaz, A.; Ordonez, H.; Jacewicz, A.; Ferrao, R.; Shuman, S.
Nucleic Acids Research (2018)

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The DNA repair repertoire of Mycobacterium smegmatis FenA includes the incision of DNA 5' flaps and the removal of 5' adenylylated products of aborted nick ligation

Journal Article

Uson, M. L.; Ghosh, S.; Shuman, S.
Journal of Bacteriology (2017)

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Characterization of Runella slithyformis HD-Pnk, a bifunctional DNA/RNA end-healing enzyme composed of an N-terminal 2',3'- phosphoesterase HD domain and a C-terminal 5'-OH polynucleotide kinase domain

Journal Article

Munir, A.; Shuman, S.
Journal of Bacteriology (2017)

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Mycobacterium smegmatis HelY is an RNA-activated ATPase/dATPase and 3'-to-5' helicase that unwinds 3'-tailed RNA duplexes and RNA:DNA hybrids

Journal Article

Uson, M. L.; Ordonez, H.; Shuman, S.
Journal of Bacteriology (2015)

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Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation

Journal Article

Ordonez, H.; Uson, M. L.; Shuman, S.
Nucleic Acids Research (2014)

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Structures of bacterial polynucleotide kinase in a Michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide