Synapse - Ghassan Abou-Alfa

Results (573)

Concordance in oncogenic alterations between the primary tumor and advanced disease: Insights into the heterogeneity of intrahepatic cholangiocarcinoma

Journal Article

McIntyre, S. M.; Preston, W. A.; Walch, H.; Sharib, J.; Kundra, R.; Sigel, C.; Lidsky, M. E.; Allen, P. J.; Morse, M. A.; Chen, W.; more...
JCO Precision Oncology (2024)

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Botensilimab plus balstilimab in relapsed/refractory microsatellite stable metastatic colorectal cancer: A phase 1 trial

Journal Article

Bullock, A. J.; Schlechter, B. L.; Fakih, M. G.; Tsimberidou, A. M.; Grossman, J. E.; Gordon, M. S.; Wilky, B. A.; Pimentel, A.; Mahadevan, D.; Balmanoukian, A. S.; more...
Nature Medicine (2024)

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Has management of intrahepatic cholangiocarcinoma evolved with the evidence? Trends and practice patterns from the National Cancer Database

Journal Article

Schleimer, L. E.; Kalvin, H. L.; Ellis, R. J.; Kingham, T. P.; Soares, K. C.; D’Angelica, M. I.; Balachandran, V. P.; Drebin, J.; Cercek, A.; Abou-Alfa, G. K.; more...
Annals of Surgical Oncology (2024)

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ATHENA: A phase 1/2 study of AZD5851, a chimeric antigen receptor (CAR) T-cell therapy directed against GPC3 in adult patients with advanced/recurrent hepatocellular carcinoma (HCC)

Meeting Abstract

Hamilton, A.; Kelley, R. K.; Li, D.; Bermejo, I. M.; Abou-Alfa, G. K.; Alese, O. B.; Al-Rajabi, R. M. T.; Babiker, H. M.; Borad, M.; Dayyani, F.; more...
Journal of Clinical Oncology (2024)

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GEMINI-Hepatobiliary: A phase 2 study of novel first-line immuno-oncology-based treatments in patients with advanced hepatobiliary cancers

Meeting Abstract

Zhou, J.; Cheng, A. L.; Ikeda, M.; Lim, H. Y.; Akce, M.; Qin, S.; Oh, D. Y.; Chan, S. L.; Xiang, J.; Qu, X.; more...
Journal of Clinical Oncology (2024)

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A phase 1/2, safety lead-in and dose expansion, open-label, multicenter trial investigating the safety, tolerability, and preliminary activity of ivosidenib in combination with nivolumab and ipilimumab in previously treated subjects with IDH1-mutated nonresectable or metastatic cholangiocarcinoma

Meeting Abstract

Kelley, R. K.; Cleary, J. M.; Sahai, V.; Baretti, M.; Bridgewater, J. A.; Hua, Z.; Gliser, C.; Bian, Y.; Abou-Alfa, G. K.
Journal of Clinical Oncology (2024)

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Phase 2 study of livmoniplimab in combination with budigalimab in patients with hepatocellular carcinoma

Meeting Abstract

Abou-Alfa, G. K.; Chiu, C. F.; Piscaglia, F.; Sangro, B.; Henkel, A.; Fang, H.; Patel, M.; Ping, Z.; Sutherland, C.; Bako, E.; more...
Journal of Clinical Oncology (2024)

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Alliance EAY191-A6: FOLFOX in combination with binimetinib as second-line therapy for patients with advanced biliary tract cancers (BTCs) with MAPK pathway alterations: A ComboMATCH treatment trial

Meeting Abstract

Shergill, A.; Liao, C. Y.; Elsaid, M. I.; Al Baghdadi, T.; Ji, Y.; Feldman, D.; George, S.; O'Reilly, E. M.; Meyerhardt, J. A.; Berg, S. A.; more...
Journal of Clinical Oncology (2024)

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Phase 2/3 study of livmoniplimab in combination with budigalimab in patients with locally advanced or metastatic hepatocellular carcinoma

Meeting Abstract

Abou-Alfa, G. K.; Bouattour, M.; Cheng, A. L.; Dayyani, F.; Khalil, D.; Li, D.; Liao, C. Y.; López, C. L.; Rimassa, L.; Deutsch, J.; more...
Journal of Clinical Oncology (2024)

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Fibrolamellar carcinoma registry: Opportunities and challenges

Meeting Abstract

Al Mahmasani, L.; Capanu, M.; Losert, K.; Lowery, M. A.; Hennessy, M.; Ray, M.; Chambers, S.; Yaqubie, A.; Zarski, A.; El Dika, I. H.; more...
Journal of Clinical Oncology (2024)

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