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Anna Mary Varghese

Results (145)

RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

Journal Article

Sethna, Z.; Guasp, P.; Reiche, C.; Milighetti, M.; Ceglia, N.; Patterson, E.; Lihm, J.; Payne, G.; Lyudovyk, O.; Rojas, L. A.; more...
Nature (2025)

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Adjuvant modified FOLFIRINOX for resected pancreatic adenocarcinoma: Clinical insights and genomic features from a large contemporary cohort

Journal Article

Keane, F.; O’Connor, C.; Moss, D.; Chou, J. F.; Perry, M. A.; Crowley, F.; Saxena, P.; Chan, A.; Schoenfeld, J. D.; Singhal, A.; more...
JNCI: Journal of the National Cancer Institute (2025)

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Long-term outcomes in patients with advanced intrahepatic cholangiocarcinoma treated with hepatic arterial infusion chemotherapy

Journal Article

Cowzer, D.; Soares, K.; Walch, H.; Gönen, M.; Boucher, T. M.; Do, R. K. G.; Harding, J. J.; Varghese, A. M.; Reidy-Lagunes, D.; Saltz, L.; more...
JNCI: Journal of the National Cancer Institute (2025)

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Pamrevlumab plus nab-paclitaxel/gemcitabine (Pam + GA) as first- and second-line therapy in metastatic pancreatic cancer (mPDAC): Results from Precision Promise (PrP) Bayesian platform trial

Meeting Abstract

Picozzi, V. J.; Varghese, A. M.; Oberstein, P. E.; Hidalgo, M.; Wolpin, B. M.; Lim, K. H.; McGlothlin, A.; Graves, T.; Detry, M. A.; Fitzgerald, M.; more...
Journal of Clinical Oncology (2025)

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Phase II trial of Pembrolizumab and OLApaRib (POLAR) maintenance for select patients (pts) with metastatic pancreatic cancer (mPC) with (A) homologous recombination deficiency (HRD), (B) non-core HRD (ncHRD) and (C) exceptional response to platinum

Meeting Abstract

Park, W.; O'Connor, C.; Chou, J.; Schwartz, C.; Larsen, M.; Varghese, A.; Yu, K.; Balogun, F.; Yang, J.; Katz, S.; more...
Annals of Oncology (2024)

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Lynch syndrome and somatic mismatch repair variants in pancreas cancer

Journal Article

O'Connor, C. A.; Harrold, E.; Lin, D.; Walch, H.; Gazzo, A.; Ranganathan, M.; Kane, S.; Keane, F.; Schoenfeld, J.; Moss, D.; more...
JAMA Oncology (2024)

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Precision Promise (PrP) Bayesian platform trial for metastatic pancreatic cancer (mPDAC): Results of the first experimental arm, SM-88 as second line therapy

Meeting Abstract

Oberstein, P. E.; Wang-Gillam, A.; Varghese, A. M.; Ko, A. H.; Hendifar, A. E.; Ocean, A. J.; McGlothlin, A.; Graves, T.; Berry, S. M.; Detry, M. A.; more...
Journal of Clinical Oncology (2024)

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BNT321, a novel monoclonal antibody targeting sialyl Lewis A: Phase 1 monotherapy and combination with mFOLFIRINOX in patients with advanced CA19-9 expressing cancers

Meeting Abstract

O'Reilly, E. M.; Bauer, T. M.; Borazanci, E. H.; Pelster, M.; Varghese, A. M.; Park, W.; Patel, M. R.; Jameson, G. S.; Larsen, M.; Chin, K.; more...
Journal of Clinical Oncology (2024)

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Precision medicine for pancreatic cancer: Characterizing the clinicogenomic landscape and outcomes of KRAS G12C-mutated disease

Journal Article

Keane, F.; Chou, J. F.; Walch, H.; Schoenfeld, J.; Singhal, A.; Cowzer, D.; Harrold, E.; O'Connor, C. A.; Park, W.; Varghese, A.; more...
JNCI: Journal of the National Cancer Institute (2024)

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Avutometinib/defactinib and gemcitabine/nab-paclitaxel combination in first-line metastatic pancreatic ductal adenocarcinoma: Initial safety and efficacy of phase 1b/2 study (RAMP 205)

Meeting Abstract

Lim, K. H.; Spencer, K. R.; Safyan, R. A.; Picozzi, V. J.; Varghese, A. M.; Siolas, D.; Perez, K.; Clift, S.; Denis, L. J.; Bhambhani, V.; more...
Journal of Clinical Oncology (2024)

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