Research Focus

Former Employee. Molecular Pharmacology Program; Research Fellow

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1. The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

   Journal Article

   Huang, G.; Zhao, X.; Wang, L.; Elf, S.; Xu, H.; Sashida, G.; Zhang, Y.; Liu, Y.; Lee, J.; Menendez, S.; more...
   Blood (2011)

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2. Previously unknown interactions between AML1 and MLL provide epigenetic regulation of gene expression in normal hematopoiesis and in leukemia

   Meeting Abstract

   Huang, G.; Elf, S.; Yan, X. M.; Wang, L.; Liu, Y.; Sashida, G.; Gural, A.; Menendez, S.; Lee, J.; Yang, Y. Y.; more...
   Blood (2008)

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3. PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis

   Journal Article

   Huang, G.; Zhang, P.; Hirai, H.; Elf, S.; Yan, X.; Chen, Z.; Koschmieder, S.; Okuno, Y.; Dayaram, T.; Growney, J. D.; more...
   Nature Genetics (2008)

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