Research Focus

Former Employee. Research Facilities; Senior Research Scientist

Recent additions – View all

1. Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 γ-secretase complexes

   Journal Article

   Placanica, L.; Tarassishin, L.; Yang, G.; Peethumnongsin, E.; Kim, S. H.; Zheng, H.; Sisodia, S. S.; Li, Y. M.
   Journal of Biological Chemistry (2009)

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2. Synthesis of antiproliferative cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: Uncovering differential susceptibilities to multidrug resistance

   Journal Article

   Eckelbarger, J. D.; Wilmot, J. T.; Epperson, M. T.; Thakur, C. S.; Shum, D.; Antczak, C.; Tarassishin, L.; Djaballah, H.; Gin, D. Y.
   Chemistry - A European Journal (2008)

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3. Deletion of presenilin 1 hydrophilic loop sequence leads to impaired γ-secretase activity and exacerbated amyloid pathology

   Journal Article

   Deng, Y.; Tarassishin, L.; Kallhoff, V.; Peethumnongsin, E.; Wu, L.; Li, Y. M.; Zheng, H.
   The Journal of Neuroscience (2006)

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