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Christine Anne Pratilas

Formats
  1. Journal Article (25)
  2. Meeting Abstract (25)
Groups
  1. Department of Medicine (45)
  2. GSK Faculty (44)
  3. Solid Tumor Oncology Division (43)
  4. Human Oncology and Pathogenesis Program (38)
  5. Sloan Kettering Institute Faculty (37)
  6. Breast Medicine Service (36)

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People
  1. Neal Rosen (36)
  2. David Solit (34)
  3. Barry Taylor (11)
  4. Yogindra Persaud (10)
  5. Ayana Sawai (9)
  6. Madhavi Tadi (9)

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Years
  1. 2015 (6)
  2. 2014 (4)
  3. 2013 (2)
  4. 2012 (6)
  5. 2011 (3)
  6. 2010 (6)

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Publications
  1. Cancer Research (22)
  2. Clinical Cancer Research (4)
  3. Journal of Clinical Oncology (3)
  4. Cancer Discovery (2)
  5. Pediatric Blood and Cancer (2)
  6. Proceedings of the National Academy of Sciences of the United States of America (2)

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Publishers
  1. American Association for Cancer Research (30)
  2. Nature Publishing Group (4)
  3. American Society of Clinical Oncology (3)
  4. Cell Press (2)
  5. National Academy of Sciences (2)
  6. Oxford University Press (2)

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Results (50)


Citation style sort is year ascending, and then by author or title. Author ascending is default.
  • An in-frame deletion in the N-terminal regulatory domain of BRAF(V600E) causes resistance to the RAF inhibitor PLX4032
    Meeting Abstract

    Poulikakos, P. I.; Persaud, Y.; Gabay, M. T.; Janakiraman, M.; Joseph, E. W.; Pratilas, C. A.; Chapman, P. B.; Rosen, N.; Solit, D. B.
    Cancer Research (2011)

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  • Concurrent loss of PTEN and RB is sufficient to confer BRAF independence in melanomas harboring V600E BRAF mutations
    Meeting Abstract

    Xing, F.; Persaud, Y.; Pratilas, C.; Janakiraman, M.; She, Q. B.; Liu, C.; Dolgalev, I.; Heguy, A.; Wolchok, J.; Cobrinik, D.; more...
    Cancer Research (2010)

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  • The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner
    Meeting Abstract

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Persaud, Y.; Xing, F.; Halilovic, E.; Viale, A.; more...
    Cancer Research (2010)

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  • Targeting the mitogen-activated protein kinase pathway: Physiological feedback and drug response
    Journal Article

    Pratilas, C. A.; Solit, D. B.
    Clinical Cancer Research (2010)

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  • The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
    Journal Article

    Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Halilovic, E.; Persaud, Y.; Xing, F.; Viale, A.; more...
    Proceedings of the National Academy of Sciences of the United States of America (2010)

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  • Genomic and biological characterization of exon 4 KRAS mutations in human cancer
    Journal Article

    Janakiraman, M.; Vakiani, E.; Zeng, Z.; Pratilas, C. A.; Taylor, B. S.; Chitale, D.; Halilovic, E.; Wilson, M.; Huberman, K.; Ricarte-Filho, J. C.; more...
    Cancer Research (2010)

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  • Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244)
    Journal Article

    Dry, J. R.; Pavey, S.; Pratilas, C. A.; Harbron, C.; Runswick, S.; Hodgson, D.; Chresta, C.; McCormack, R.; Byrne, N.; Cockerill, M.; more...
    Cancer Research (2010)

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  • Genetic predictors of MEK dependence in V600E BRAF mutant melanoma
    Meeting Abstract

    Xing, F.; Pratilas, C.; Persaud, Y.; Janakiraman, M.; Houghton, A.; Rosen, N.; Solit, D.
    Cancer Research (2009)

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  • Amplification of wild-type BRAF in melanoma is associated with activation of RAF-MEK-ERK signaling and MEK-dependence
    Meeting Abstract

    Blumenthal, E.; Poulikakos, P. I.; Tadi, M.; Grbovic-Huezo, O.; Taylor, B. S.; Janakiraman, M.; Leversha, M.; Viale, A.; Solit, D. B.; Rosen, N.; more...
    Cancer Research (2009)

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  • V600EBRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
    Journal Article

    Pratilas, C. A.; Taylor, B. S.; Ye, Q.; Viale, A.; Sander, C.; Solit, D. B.; Rosen, N.
    Proceedings of the National Academy of Sciences of the United States of America (2009)

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