Synapse - Darren Veach

Results (99)

Fluorine-labeled dasatinib nanoformulations as targeted molecular imaging probes in a PDGFB-driven murine glioblastoma model

Journal Article

Benezra, M.; Hambardzumyan, D.; Penate-Medina, O.; Veach, D. R.; Pillarsetty, N.; Smith-Jones, P.; Phillips, E.; Ozawa, T.; Zanzonico, P. B.; Longo, V.; more...
NeoPlasia (2012)

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Imatinib resistance and microcytic erythrocytosis in a Kit(V558Δ;T669I/+) gatekeeper-mutant mouse model of gastrointestinal stromal tumor

Journal Article

Bosbach, B.; Deshpande, S.; Rossi, F.; Shieh, J.H.; Sommer, G.; de Stanchina, E.; Veach, D. R.; Scandura, J. M.; Manova-Todorova, K.; Moore, M. A. S.; more...
Proceedings of the National Academy of Sciences of the United States of America (2012)

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Dosimetry of 18F-labeled tyrosine kinase inhibitor SKI-249380, a dasatinib-tracer for PET imaging

Journal Article

Dunphy, M. P. S.; Zanzonico, P.; Veach, D.; Somwar, R.; Pillarsetty, N.; Lewis, J.; Larson, S.
Molecular Imaging and Biology (2012)

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Synthesis of fluorinated analogs of abiraterone, a mechanism-based inhibitor of CYP17A1 for castration resistant prostate cancer therapy

Meeting Abstract

Veach, D. R.; Evans, M.; Sawyers, C. L.; Larson, S. M.
Journal of Labelled Compounds and Radiopharmaceuticals (2011)

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A magnetic bead-based protein kinase assay with dual detection techniques

Journal Article

Zhou, G.; Sylvester, J. E.; Wu, D.; Veach, D. R.; Kron, S. J.
Analytical Biochemistry (2011)

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Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib

Journal Article

Rossi, F.; Yozgat, Y.; de Stanchina, E.; Veach, D.; Clarkson, B.; Manova, K.; Giancotti, F. G.; Antonescu, C. R.; Besmer, P.
Molecular Cancer Research (2010)

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Cell treatment and lysis in 96-well filter-bottom plates for screening Bcr-Abl activity and inhibition in whole-cell extracts

Journal Article

Mand, M. R.; Wu, D.; Veach, D. R.; Kron, S. J.
Journal of Biomolecular Screening (2010)

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(124)I-Iodopyridopyrimidinone for PET of Abl kinase-expressing tumors in vivo

Journal Article

Doubrovin, M.; Kochetkova, T.; Santos, E.; Veach, D. R.; Smith-Jones, P.; Pillarsetty, N.; Balatoni, J.; Bornmann, W.; Gelovani, J.; Larson, S. M.
Journal of Nuclear Medicine (2010)

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Mechanisms of sunitinib resistance in gastrointestinal stromal tumors harboring KIT(AY502-3ins) mutation: An in vitro mutagenesis screen for drug resistance

Journal Article

Guo, T.; Hajdu, M.; Agaram, N. P.; Shinoda, H.; Veach, D.; Clarkson, B. D; Maki, R. G.; Singer, S.; DeMatteo, R. P.; Besmer, P.; more...
Clinical Cancer Research (2009)

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Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: Toward selective Abl inhibitors

Journal Article

Antczak, C.; Veach, D. R.; Ramirez, C. N.; Minchenko, M. A.; Shum, D.; Calder, P. A.; Frattini, M. G.; Clarkson, B.; Djaballah, H.
Bioorganic & Medicinal Chemistry Letters (2009)

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