Synapse - Devin Mcavoy

Results (36)

Results from first-in-human phase I study of a novel CD19-1XX chimeric antigen receptor with calibrated signaling in Large B-cell lymphoma

Journal Article

Park, J. H.; Palomba, M. L.; Perica, K.; Devlin, S. M.; Shah, G.; Dahi, P. B.; Lin, R. J.; Salles, G.; Scordo, M.; Nath, K.; more...
Journal of Clinical Oncology (2025)

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Impact of age and acute GVHD on thymic reconstitution post-HCT: Insights from multicenter immune monitoring of pediatric and young adult patients

Meeting Abstract

McAvoy, D.; Velardi, E.; Kunstek, H.; Barbarito, G.; Taviani, A.; Galaverna, F.; Klein, E.; Lucas, A. T.; de Koning, C.; Hosszu, K.; more...
Cytotherapy (2025)

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T-cell phenotypes of CD28 Vs 4-1BB CD19 specific Car T-cells for patients with B-ALL

Meeting Abstract

Lucas, A. T.; Shahid, S.; McAvoy, D.; Hosszu, K.; Wang, X.; Boelens, J. J.; Curran, K. J.
Cytotherapy (2025)

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Temporal relationships between dendritic cells, cytokines, and Tregs in pre-GVHD pediatric patients

Meeting Abstract

Hosszu, K.; McAvoy, D.; Klein, E.; Singh, K. H.; Habiba, U.; Curran, K. J.; Cancio, M.; Scaradavou, A.; Kung, A.; Oved, J.; more...
Cytotherapy (2025)

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Streamlined production of tumor-associated antigen-specific T cells (TAAT) from antigen-naive donors in a GREX device using autologous monocyte-derived dendritic cells (MODC) manufactured in the same device as antigen presenting cells (APC)

Meeting Abstract

Vozniuk, D.; Dontsova, M.; Secka, O.; Hosszu, K.; McAvoy, D.; Ntrivalas, E.; Kolovrat, A.; Nikitina, E.; Vladimirov, A.; Feuer, E.; more...
Cytotherapy (2025)

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Rapid manufacturing of monocyte-derived dendritic cells (MODC) in a GREX device with a seamless transition to the production of tumor-associated antigen-specific T cells (TAAT) in the same device

Meeting Abstract

Vozniuk, D.; Dontsova, M.; Secka, O.; Hosszu, K.; McAvoy, D.; Ntrivalas, E.; Kolovrat, A.; Nikitina, E.; Vladimirov, A.; Feuer, E.; more...
Cytotherapy (2025)

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Allogeneic off-the-shelf CAR T-cell therapy for relapsed or refractory B-cell malignancies

Journal Article

Shahid, S.; Prockop, S. E.; Flynn, G. C.; Mauguen, A.; White, C. O.; Bieler, J.; McAvoy, D.; Hosszu, K.; Cancio, M. I.; Jakubowski, A. A.; more...
Blood Advances (2025)

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Phase I trial of MCARH109, a G protein-coupled receptor class C group 5 member D (GPRC5D)-targeted chimeric antigen receptor T-cell therapy for multiple myeloma: An updated analysis

Journal Article

Jurgens, E. M.; Firestone, R. S.; Chaudhari, J.; Hosszu, K.; Devlin, S. M.; Shah, U. A.; Landa, J.; McAvoy, D. P.; Lesokhin, A. M.; Korde, N.; more...
Journal of Clinical Oncology (2025)

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A Proof-of-principle of split-course bridging radiotherapy (SC-BRT) prior to CAR T-cell therapies for relapsed or refractory B-cell lymphomas: A phase 1a pilot cohort