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Michael Angelo Lopez

  1. "Sloan Kettering Institute Postdocs"
Formats
  1. Meeting Abstract (5)
  2. Journal Article (4)
Groups
  1. Center for Hematologic Malignancies (9)
  2. GSK Faculty (9)
  3. Hematologic Malignancies Research (9)
  4. Molecular Pharmacology and Chemistry Program Faculty (9)
  5. Sloan Kettering Institute Faculty (9)
  6. Sloan Kettering Institute Postdocs (9)

More Groups

People
  1. Michel Sadelain (8)
  2. Nayan Jain (7)
  3. Richard Koche (7)
  4. Zeguo Zhao (7)
  5. Anton Dobrin (4)
  6. Archana Iyer (4)

More People

Years
  1. 2024 (1)
  2. 2023 (2)
  3. 2022 (2)
  4. 2021 (2)
  5. 2020 (2)
Publications
  1. Cancer Research (2)
  2. Molecular Therapy (2)
  3. ACS Chemical Biology (1)
  4. Blood (1)
  5. Cancer Cell (1)
  6. Cancer Discovery (1)

More Publications

Publishers
  1. American Association for Cancer Research (3)
  2. Nature Publishing Group (3)
  3. American Chemical Society (1)
  4. American Society of Hematology (1)
  5. Cell Press (1)

Results (9)

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  • Disruption of SUV39H1-mediated H3K9 methylation sustains CAR T-cell function
    Journal Article

    Jain, N.; Zhao, Z.; Koche, R. P.; Antelope, C.; Gozlan, Y.; Montalbano, A.; Brocks, D.; Lopez, M.; Dobrin, A.; Shi, Y.; more...
    Cancer Discovery (2024)

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  • Cooperative CAR targeting to selectively eliminate AML and minimize escape
    Journal Article

    Haubner, S.; Mansilla-Soto, J.; Nataraj, S.; Kogel, F.; Chang, Q.; de Stanchina, E.; Lopez, M.; Ng, M. R.; Fraser, K.; Subklewe, M.; more...
    Cancer Cell (2023)

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  • TET2 guards against unchecked BATF3-induced CAR T cell expansion
    Journal Article

    Jain, N.; Zhao, Z.; Feucht, J.; Koche, R.; Iyer, A.; Dobrin, A.; Mansilla-Soto, J.; Yang, J.; Zhan, Y.; Lopez, M.; more...
    Nature (2023)

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  • SUV39H1 disruption enhances the persistence and anti-tumor efficacy of CD28-costimulated human CAR T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Koche, R.; Gozlan, Y.; Brocks, D.; Raveh-Sadka, T.; Wells, D.; Dobrin, A.; Shi, Y.; Lopez, M.; more...
    Cancer Research (2022)

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  • Disruption of H3K9me3-mediated gene silencing augments CAR T cell functional persistence
    Meeting Abstract

    Jain, N.; Zhao, Z.; Koche, R.; Gozlan, Y.; Brocks, D.; Raveh-Sadka, T.; Wells, D.; Dobrin, A.; Shi, Y.; Lopez, M.; more...
    Molecular Therapy (2022)

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  • Emergence of a hyper-proliferative phenotype in TET2 edited human CAR T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Iyer, A.; Lopez, M.; Feucht, J.; Koche, R.; Yang, J.; Zhan, Y.; Sadelain, M.
    Cancer Research (2021)

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  • CAR design and expression determine hyper-proliferative states in TET2 deficient T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Iyer, A.; Lopez, M.; Feucht, J.; Koche, R.; Yang, J.; Zhan, Y.; Sadelain, M.
    Molecular Therapy (2021)

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  • Loss of (TET2) uncouples proliferative and effector functions in CAR T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Iyer, A. S.; Lopez, M.; Feucht, J.; Koche, R. P.; Zhan, Y.; Sadelain, M.
    Blood (2020)

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  • Bisubstrate-type chemical probes identify GRP94 as a potential target of cytosine-containing adenosine analogs
    Journal Article

    Pechalrieu, D.; Assemat, F.; Halby, L.; Marcellin, M.; Yan, P.; Chaoui, K.; Sharma, S.; Chiosis, G.; Burlet-Schiltz, O.; Arimondo, P. B.; more...
    ACS Chemical Biology (2020)

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