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Michael Angelo Lopez

Formats
  1. Meeting Abstract (6)
  2. Journal Article (5)
Groups
  1. Center for Hematologic Malignancies (10)
  2. GSK Faculty (10)
  3. Hematologic Malignancies Research (10)
  4. Molecular Pharmacology and Chemistry Program Faculty (10)
  5. Sloan Kettering Institute Faculty (10)
  6. Department of Medicine (9)

More Groups

People
  1. Michel Sadelain (9)
  2. Nayan Jain (7)
  3. Richard Koche (7)
  4. Zeguo Zhao (7)
  5. Anton Dobrin (5)
  6. Archana Iyer (4)

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Years
  1. 2024 (2)
  2. 2023 (2)
  3. 2022 (3)
  4. 2021 (2)
  5. 2020 (2)
Publications
  1. Molecular Therapy (3)
  2. Cancer Research (2)
  3. ACS Chemical Biology (1)
  4. Blood (1)
  5. Blood Cancer Journal (1)
  6. Cancer Cell (1)

More Publications

Publishers
  1. Nature Publishing Group (5)
  2. American Association for Cancer Research (3)
  3. American Chemical Society (1)
  4. American Society of Hematology (1)
  5. Cell Press (1)

Results (11)

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  • CAR T-cell-derived TNF drives cytokine release syndrome and enhances M1 macrophage differentiation
    Meeting Abstract

    Lindenbergh, P. L.; Giavridis, T.; Vivier, O.; Lopez, M.; Dobrin, A.; Sadelain, M.
    Molecular Therapy (2024)

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  • Disruption of SUV39H1-mediated H3K9 methylation sustains CAR T-cell function
    Journal Article

    Jain, N.; Zhao, Z.; Koche, R. P.; Antelope, C.; Gozlan, Y.; Montalbano, A.; Brocks, D.; Lopez, M.; Dobrin, A.; Shi, Y.; more...
    Cancer Discovery (2024)

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  • Cooperative CAR targeting to selectively eliminate AML and minimize escape
    Journal Article

    Haubner, S.; Mansilla-Soto, J.; Nataraj, S.; Kogel, F.; Chang, Q.; de Stanchina, E.; Lopez, M.; Ng, M. R.; Fraser, K.; Subklewe, M.; more...
    Cancer Cell (2023)

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  • TET2 guards against unchecked BATF3-induced CAR T cell expansion
    Journal Article

    Jain, N.; Zhao, Z.; Feucht, J.; Koche, R.; Iyer, A.; Dobrin, A.; Mansilla-Soto, J.; Yang, J.; Zhan, Y.; Lopez, M.; more...
    Nature (2023)

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  • SUV39H1 disruption enhances the persistence and anti-tumor efficacy of CD28-costimulated human CAR T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Koche, R.; Gozlan, Y.; Brocks, D.; Raveh-Sadka, T.; Wells, D.; Dobrin, A.; Shi, Y.; Lopez, M.; more...
    Cancer Research (2022)

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  • In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors
    Journal Article

    Aktas Samur, A.; Fulciniti, M.; Avet-Loiseau, H.; Lopez, M. A.; Derebail, S.; Corre, J.; Minvielle, S.; Magrangeas, F.; Moreau, P.; Anderson, K. C.; more...
    Blood Cancer Journal (2022)

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  • Disruption of H3K9me3-mediated gene silencing augments CAR T cell functional persistence
    Meeting Abstract

    Jain, N.; Zhao, Z.; Koche, R.; Gozlan, Y.; Brocks, D.; Raveh-Sadka, T.; Wells, D.; Dobrin, A.; Shi, Y.; Lopez, M.; more...
    Molecular Therapy (2022)

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  • Emergence of a hyper-proliferative phenotype in TET2 edited human CAR T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Iyer, A.; Lopez, M.; Feucht, J.; Koche, R.; Yang, J.; Zhan, Y.; Sadelain, M.
    Cancer Research (2021)

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  • CAR design and expression determine hyper-proliferative states in TET2 deficient T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Iyer, A.; Lopez, M.; Feucht, J.; Koche, R.; Yang, J.; Zhan, Y.; Sadelain, M.
    Molecular Therapy (2021)

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  • Loss of (TET2) uncouples proliferative and effector functions in CAR T cells
    Meeting Abstract

    Jain, N.; Zhao, Z.; Iyer, A. S.; Lopez, M.; Feucht, J.; Koche, R. P.; Zhan, Y.; Sadelain, M.
    Blood (2020)

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