Groups

Research Focus

Structural Biology; Senior Research Scientist

Recent additions – View all

1. cGAMP-activated cGAS–STING signaling: Its bacterial origins and evolutionary adaptation by metazoans

   Review

   Patel, D. J.; Yu, Y.; Xie, W.
   Nature Structural and Molecular Biology (2023)

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2. Bacterial origins of cyclic nucleotide-activated antiviral immune signaling

   Review

   Patel, D. J.; Yu, Y.; Jia, N.
   Molecular Cell (2022)

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3. Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes

   Journal Article

   Yu, Y.; Li, S.; Ser, Z.; Kuang, H.; Than, T.; Guan, D.; Zhao, X.; Patel, D. J.
   Proceedings of the National Academy of Sciences of the United States of America (2022)

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