Research Focus

Former Employee. Human Oncology and Pathogenesis Program; Visiting Investigator

Recent additions – View all

1. Defining an optimal dual-targeted CAR T-cell therapy approach simultaneously targeting BCMA and GPRC5D to prevent BCMA escape– Driven relapse in multiple myeloma

   Journal Article

   de Larrea, C. F.; Staehr, M.; Lopez, A. V.; Ng, K. Y.; Chen, Y.; Godfrey, W. D.; Purdon, T. J.; Ponomarev, V.; Wendel, H. G.; Brentjens, R. J.; more...
   Blood Cancer Discovery (2020)

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2. Optimal dual-targeted CAR construct simultaneously targeting BCMA and GPRC5D prevents BCMA-escape driven relapse in multiple myeloma

   Meeting Abstract

   Fernandez de Larrea, C.; Staehr, M.; Lopez, A.; Chen, Y.; Purdon, T. J.; Ng, K. Y.; Wendel, H.; Brentjens, R. J.; Smith, E. L.
   Blood (2019)

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3. GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells

   Journal Article

   Smith, E. L.; Harrington, K.; Staehr, M.; Masakayan, R.; Jones, J.; Long, T. J.; Ng, K. Y.; Ghoddusi, M.; Purdon, T. J.; Wang, X.; more...
   Science Translational Medicine (2019)

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