Synapse - Kristian Helin

Results (35)

MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells

Journal Article

Müller, I.; Moroni, A. S.; Shlyueva, D.; Sahadevan, S.; Schoof, E. M.; Radzisheuskaya, A.; Højfeldt, J. W.; Tatar, T.; Koche, R. P.; Huang, C.; more...
Nature Communications (2021)

Fulltext@MSK | Save

ChIP-sequencing of TET proteins

Journal Article

Rasmussen, K. D.; Helin, K.
Methods in Molecular Biology (2021)

Fulltext@MSK | Save

Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis

Journal Article

Radzisheuskaya, A.; Shliaha, P. V.; Grinev, V. V.; Shlyueva, D.; Damhofer, H.; Koche, R.; Gorshkov, V.; Kovalchuk, S.; Zhan, Y.; Rodriguez, K. L.; more...
Molecular Cell (2021)

Fulltext@MSK | Save

PRMT5 inhibition modulates E2F1 methylation and gene-regulatory networks leading to therapeutic efficacy in JAK2(V617F)-mutant MPN

Journal Article

Pastore, F.; Bhagwat, N.; Pastore, A.; Radzisheuskaya, A.; Karzai, A.; Krishnan, A.; Li, B.; Bowman, R. L.; Xiao, W.; Viny, A. D.; more...
Cancer Discovery (2020)

Fulltext@MSK | Save

Mutant FOXL2(C134W) hijacks SMAD4 and SMAD2/3 to drive adult granulosa cell tumors

Journal Article

Weis-Banke, S. E.; Lerdrup, M.; Kleine-Kohlbrecher, D.; Mohammad, F.; Sidoli, S.; Jensen, O. N.; Yanase, T.; Nakamura, T.; Iwase, A.; Stylianou, A.; more...
Cancer Research (2020)

Fulltext@MSK | Save

PR-DUB maintains the expression of critical genes through FOXK1/2- A nd ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination

Journal Article

Kolovos, P.; Nishimura, K.; Sankar, A.; Sidoli, S.; Cloos, P. A.; Helin, K.; Christensen, J.
Genome Research (2020)

Fulltext@MSK | Save

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

Research Letter

Sankar, A.; Lerdrup, M.; Manaf, A.; Johansen, J. V.; Gonzalez, J. M.; Borup, R.; Blanshard, R.; Klungland, A.; Hansen, K.; Andersen, C. Y.; more...
Nature Cell Biology (2020)

Fulltext@MSK | Save

Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary

Journal Article

Kim, S. H.; Da Cruz Paula, A.; Basili, T.; Dopeso, H.; Bi, R.; Pareja, F.; da Silva, E. M.; Gularte-Mérida, R.; Sun, Z.; Fujisawa, S.; more...
Nature Communications (2020)

Fulltext@MSK | Save

PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia

Journal Article

Radzisheuskaya, A.; Shliaha, P. V.; Grinev, V.; Lorenzini, E.; Kovalchuk, S.; Shlyueva, D.; Gorshkov, V.; Hendrickson, R. C.; Jensen, O. N.; Helin, K.
Nature Structural and Molecular Biology (2019)

Fulltext@MSK | Save

A functional link between nuclear RNA decay and transcriptional control mediated by the polycomb repressive complex 2

Journal Article

Garland, W.; Comet, I.; Wu, M.; Radzisheuskaya, A.; Rib, L.; Vitting-Seerup, K.; Lloret-Llinares, M.; Sandelin, A.; Helin, K.; Jensen, T. H.
Cell Reports (2019)

Fulltext@MSK | Save