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Sophie Shifman

Formats
  1. Journal Article (6)
  2. Meeting Abstract (3)
  3. Research Letter (1)
Groups
  1. GSK Faculty (10)
  2. Sloan Kettering Institute Postdocs (10)
  3. Department of Medicine (9)
  4. Early Drug Development Service (9)
  5. Solid Tumor Oncology Division (9)
  6. Center for Molecular Imaging and Biotechnology (CMIB) (8)

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People
  1. Emiliano Cocco (10)
  2. Maurizio Scaltriti (10)
  3. David Hyman (9)
  4. Alexander Drilon (7)
  5. Michael Berger (7)
  6. Alison Schram (6)

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Years
  1. 2022 (1)
  2. 2021 (1)
  3. 2020 (4)
  4. 2019 (3)
  5. 2018 (1)
Publications
  1. Cancer Discovery (2)
  2. Cancer Research (2)
  3. Clinical Cancer Research (2)
  4. Cell Reports (1)
  5. Nature Communications (1)
  6. Nature Medicine (1)

More Publications

Publishers
  1. American Association for Cancer Research (6)
  2. Nature Publishing Group (2)
  3. American Association for the Advancement of Science (1)
  4. Cell Press (1)

Results (10)

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  • The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers
    Journal Article

    Rosen, E. Y.; Won, H. H.; Zheng, Y.; Cocco, E.; Selcuklu, D.; Gong, Y.; Friedman, N. D.; de Bruijn, I.; Sumer, O.; Bielski, C. M.; more...
    Nature Communications (2022)

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  • TRK XDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
    Journal Article

    Cocco, E.; Lee, J. E.; Kannan, S.; Schram, A. M.; Won, H. H.; Shifman, S.; Kulick, A.; Baldino, L.; Toska, E.; Arruabarrena-Aristorena, A.; more...
    Cancer Discovery (2021)

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  • TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
    Meeting Abstract

    Cocco, E.; Lee, J. E.; Kannan, S.; Schram, A. M.; Won, H. H.; Shifman, S.; Kulick, A.; Baldino, L.; Toska, E.; Arena, S.; more...
    Cancer Research (2020)

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  • Landscape and outcome of TRK fusion-positive cancers
    Meeting Abstract

    Rosen, E. Y.; Goldman, D. A.; Hechtman, J. F.; Benayed, R.; Schram, A. M.; Cocco, E.; Shifman, S.; Gong, Y.; Kundra, R.; Solomon, J. P.; more...
    Clinical Cancer Research (2020)

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  • HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers
    Journal Article

    Li, B. T.; Michelini, F.; Misale, S.; Cocco, E.; Baldino, L.; Cai, Y.; Shifman, S.; Tu, H. Y.; Myers, M. L.; Xu, C.; more...
    Cancer Discovery (2020)

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  • TRK fusions are enriched in cancers with uncommon histologies and the absence of canonical driver mutations
    Journal Article

    Rosen, E. Y.; Goldman, D. A.; Hechtman, J. F.; Benayed, R.; Schram, A. M.; Cocco, E.; Shifman, S.; Gong, Y.; Kundra, R.; Solomon, J. P.; more...
    Clinical Cancer Research (2020)

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  • Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation
    Meeting Abstract

    Cocco, E.; Kulick, A.; Misale, S.; Yaeger, R.; Razavi, P.; Won, H. H.; Ptashkin, R.; Hechtman, J. F.; Toska, E.; Cownie, J.; more...
    Cancer Research (2019)

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  • Resistance to TRK inhibition mediated by convergent MAPK pathway activation
    Research Letter

    Cocco, E.; Schram, A. M.; Kulick, A.; Misale, S.; Won, H. H.; Yaeger, R.; Razavi, P.; Ptashkin, R.; Hechtman, J. F.; Toska, E.; more...
    Nature Medicine (2019)

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  • PI3K inhibition activates SGK1 via a feedback loop to promote chromatin-based regulation of ER-dependent gene expression
    Journal Article

    Toska, E.; Castel, P.; Chhangawala, S.; Arruabarrena-Aristorena, A.; Chan, C.; Hristidis, V. C.; Cocco, E.; Sallaku, M.; Xu, G.; Park, J.; more...
    Cell Reports (2019)

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  • Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)
    Journal Article

    Cocco, E.; Carmona, F. J.; Razavi, P.; Won, H. H.; Cai, Y.; Rossi, V.; Chan, C.; Cownie, J.; Soong, J.; Toska, E.; more...
    Science Signaling (2018)

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