Synapse - David Solit

Results (783)

KRAS and BRAF: Drug targets and predictive biomarkers

Journal Article

Vakiani, E.; Solit, D. B.
Journal of Pathology (2011)

Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in Met-amplified tumor cells with or without resistance to selective MET inhibition

Journal Article

Bachleitner-Hofmann, T.; Sun, M. Y.; Chen, C. T.; Liska, D.; Zeng, Z.; Viale, A.; Olshen, A. B.; Mittlboeck, M.; Christensen, J. G.; Rosen, N.; more...
Clinical Cancer Research (2011)

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Antitumor activity of SNX-2112, a synthetic heat shock protein 90 inhibitor, in malignancies with amplification of the MET oncogene

Meeting Abstract

Bachleitner-Hofmann, T.; Sun, M. Y.; Chen, C.; Zeng, Z.; Viale, A.; Olshen, A.; Christensen, J. G.; Rosen, N.; Solit, D. B.; Weiser, M. R.
Journal of Clinical Oncology (2010)

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Concurrent loss of PTEN and RB is sufficient to confer BRAF independence in melanomas harboring V600E BRAF mutations

Meeting Abstract

Xing, F.; Persaud, Y.; Pratilas, C.; Janakiraman, M.; She, Q. B.; Liu, C.; Dolgalev, I.; Heguy, A.; Wolchok, J.; Cobrinik, D.; more...
Cancer Research (2010)

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Frequency of somatic mutations in high grade urothelial carcinomas

Meeting Abstract

Lin, O.; Solit, D.; Al-Almadie, H.; Heguy, A.; Ishill, N.; Reuter, V. E.; Millowksy, M.
Modern Pathology (2010)

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Clinical implications of selected somatic mutations in the recurrence of invasive urothelial carcinomas

Meeting Abstract

Lin, O.; Solit, D.; Al-Ahmadie, H.; Heguy, A.; Reuter, V. E.; Ishill, N.; Milowsky, M.
Laboratory Investigation (2010)

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Correlation of selected somatic mutations and pathologic stage in high grade urothelial carcinomas

Meeting Abstract

Lin, O.; Solit, D.; Al-Ahmadie, H.; Heguy, A.; Reuter, V. E.; Ishill, N. M.; Milowsky, M.
Laboratory Investigation (2010)

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The pan-RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF mutant-selective manner

Meeting Abstract

Joseph, E. W.; Pratilas, C. A.; Poulikakos, P. I.; Tadi, M.; Wang, W.; Taylor, B. S.; Persaud, Y.; Xing, F.; Halilovic, E.; Viale, A.; more...
Cancer Research (2010)

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Genetic determinants of AKT-dependence in epithelial ovarian cancer

Meeting Abstract

Hanrahan, A. J.; Scarperi, S.; Sakr, R. A.; Westfal, M. L.; Godsell, J.; Janakiraman, M.; Levine, D. A.; She, Q. B.; Rosen, N.; Solit, D. B.
Cancer Research (2010)

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Unique morphologic characteristics of high grade urothelial carcinoma with fibroblast growth factor receptor-3 (FGFR3) gene mutations

Meeting Abstract

Al-Ahmadie, H. A.; Liu, O.; Tyer, G. V.; Heguy, A.; Gopalan, A.; Fine, S. W.; Tiekoo, S. K.; Hanrahan, A. J.; Bajorin, D. F.; Reuter, V. E.; more...
Modern Pathology (2010)

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