Synapse - Taha Merghoub

Results (364)

Combination of cyclophosphamide chemotherapy with immune modulation overcomes resistance to checkpoint blockade in a pre-clinical melanoma model

Meeting Abstract

Betof Warner, A.; Hirschhorn, D.; Mangarin, L. M.; Hamadene, L.; Cohen, A. D.; Rizzuto, G. A.; Wolchok, J. D.; Merghoub, T.
Cancer Research (2021)

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Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers

Journal Article

Caushi, J. X.; Zhang, J.; Ji, Z.; Vaghasia, A.; Zhang, B.; Hsiue, E. H. C.; Mog, B. J.; Hou, W.; Justesen, S.; Blosser, R.; more...
Nature (2021)

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Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8(+) T cells in tumors

Journal Article

Xu, S.; Chaudhary, O.; Rodríguez-Morales, P.; Sun, X.; Chen, D.; Zappasodi, R.; Xu, Z.; Pinto, A. F. M.; Williams, A.; Schulze, I.; more...
Immunity (2021)

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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

Journal Article

Lu, S. X.; De Neef, E.; Thomas, J. D.; Sabio, E.; Rousseau, B.; Gigoux, M.; Knorr, D. A.; Greenbaum, B.; Elhanati, Y.; Hogg, S. J.; more...
Cell (2021)

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Tim-4(+) cavity-resident macrophages impair anti-tumor CD8(+) T cell immunity

Journal Article

Chow, A.; Schad, S.; Green, M. D.; Hellmann, M. D.; Allaj, V.; Ceglia, N.; Zago, G.; Shah, N. S.; Sharma, S. K.; Mattar, M.; more...
Cancer Cell (2021)

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Rational engineering of recombinant modified vaccinia virus Ankara to enhance both innate and adaptive immunity for cancer immunotherapy

Meeting Abstract

Yang, N.; Wang, Y.; Liu, S.; Luna, J.; Rossi, A.; Mazo, G.; Tan, A.; Wang, J.; Yan, W.; Choi, J.; more...
Journal of Investigative Dermatology (2021)

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Metastasis and immune evasion from extracellular cGAMP hydrolysis

Journal Article

Li, J.; Duran, M. A.; Dhanota, N.; Chatila, W. K.; Bettigole, S. E.; Kwon, J.; Sriram, R. K.; Humphries, M. P.; Salto-Tellez, M.; James, J. A.; more...
Cancer Discovery (2021)

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Phase II single-arm study of durvalumab and tremelimumab with concurrent radiotherapy in patients with mismatch repair-proficient metastatic colorectal cancer

Journal Article

Segal, N. H.; Cercek, A.; Ku, G.; Wu, A. J.; Rimner, A.; Khalil, D. N.; Reidy-Lagunes, D.; Cuaron, J.; Yang, T. J.; Weiser, M. R.; more...
Clinical Cancer Research (2021)

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CTLA-4 blockade drives loss of T(reg) stability in glycolysis-low tumours

Journal Article

Zappasodi, R.; Serganova, I.; Cohen, I. J.; Maeda, M.; Shindo, M.; Senbabaoglu, Y.; Watson, M. J.; Leftin, A.; Maniyar, R.; Verma, S.; more...
Nature (2021)

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Targeting phosphatidylserine enhances the anti-tumor response to tumor-directed radiation therapy in a preclinical model of melanoma

Journal Article

Budhu, S.; Giese, R.; Gupta, A.; Fitzgerald, K.; Zappasodi, R.; Schad, S.; Hirschhorn, D.; Campesato, L. F.; De Henau, O.; Gigoux, M.; more...
Cell Reports (2021)

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