Synapse - Taha Merghoub

Results (364)

Neoadjuvant PD-1 blockade in resectable lung cancer

Journal Article

Forde, P. M.; Chaft, J. E.; Smith, K. N.; Anagnostou, V.; Cottrell, T. R.; Hellmann, M. D.; Zahurak, M.; Yang, S. C.; Jones, D. R.; Broderick, S.; more...
New England Journal of Medicine (2018)

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Non-conventional inhibitory CD4(+)Foxp3(−)PD-1(hi) T cells as a biomarker of immune checkpoint blockade activity

Journal Article

Zappasodi, R.; Budhu, S.; Hellmann, M. D.; Postow, M. A.; Senbabaoglu, Y.; Manne, S.; Gasmi, B.; Liu, C.; Zhong, H.; Li, Y.; more...
Cancer Cell (2018)

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The combination of intratumoral delivery of inactivated modified vaccinia virus Ankara with systemic delivery of immune checkpoint blockade enhances antitumor immunity

Meeting Abstract

Wang, W.; Dai, P.; Yang, N.; Wang, Y.; Shuman, S.; Merghoub, T.; Wolchok, J.; Deng, L.
Journal of Investigative Dermatology (2018)

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Genomic features of response to combination immunotherapy in patients with advanced non-small-cell lung cancer

Journal Article

Hellmann, M. D.; Nathanson, T.; Rizvi, H.; Creelan, B. C.; Sanchez-Vega, F.; Ahuja, A.; Ni, A.; Novik, J. B.; Mangarin, L. M. B.; Abu-Akeel, M.; more...
Cancer Cell (2018)

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Using LIBS to diagnose melanoma in biomedical fluids deposited on solid substrates: Limits of direct spectral analysis and capability of machine learning

Journal Article

Gaudiuso, R.; Ewusi-Annan, E.; Melikechi, N.; Sun, X.; Liu, B.; Campesato, L. F.; Merghoub, T.
Spectrochimica Acta - Part B Atomic Spectroscopy (2018)

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Pre-existing immunity to oncolytic virus potentiates its immunotherapeutic efficacy

Journal Article

Ricca, J. M.; Oseledchyk, A.; Walther, T.; Liu, C.; Mangarin, L.; Merghoub, T.; Wolchok, J. D.; Zamarin, D.
Molecular Therapy (2018)

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Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody

Journal Article

Gombos, R. B.; Gonzalez, A.; Manrique, M.; Chand, D.; Savitsky, D.; Morin, B.; Breous-Nystrom, E.; Dupont, C.; Ward, R. A.; Mundt, C.; more...
PLoS ONE (2018)

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PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy

Journal Article

Zamarin, D.; Ricca, J. M.; Sadekova, S.; Oseledchyk, A.; Yu, Y.; Blumenschein, W. M.; Wong, J.; Gigoux, M.; Merghoub, T.; Wolchok, J. D.
Journal of Clinical Investigation (2018)

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Cancer-germline antigen expression discriminates clinical outcome to CTLA-4 blockade

Journal Article

Shukla, S. A.; Bachireddy, P.; Schilling, B.; Galonska, C.; Zhan, Q.; Bango, C.; Langer, R.; Lee, P. C.; Gusenleitner, D.; Keskin, D. B.; more...
Cell (2018)

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Emerging concepts for immune checkpoint blockade-based combination therapies

Journal Article

Zappasodi, R.; Merghoub, T.; Wolchok, J. D.
Cancer Cell (2018)

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