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Alison Elizabeth Smith

Formats
  1. Journal Article (3)
  2. Meeting Abstract (3)
Groups
  1. Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center (6)
  2. Breast Medicine Service (6)
  3. Department of Medicine (6)
  4. GSK Faculty (6)
  5. Human Oncology and Pathogenesis Program (6)
  6. MSK Grad Students (6)

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People
  1. Sarat Chandarlapaty (6)
  2. David Solit (3)
  3. Jorge Reis-Filho (3)
  4. Achim Jungbluth (2)
  5. Alissa Brandes (2)
  6. Anastasios Papanastasiou (2)

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Years
  1. 2025 (1)
  2. 2022 (1)
  3. 2021 (1)
  4. 2020 (1)
  5. 2018 (2)
Publications
  1. Cancer Research (3)
  2. Nature Communications (2)
  3. Nature Genetics (1)
Publishers
  1. American Association for Cancer Research (3)
  2. Nature Publishing Group (3)

Results (6)

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  • Loss of KMT2C or KMT2D primes urothelium for tumorigenesis and redistributes KMT2A-menin to bivalent promoters
    Journal Article

    Wang, N.; Pachai, M. R.; Li, D.; Lee, C. J.; Warda, S.; Khudoynazarova, M. N.; Cho, W. H.; Xie, G.; Shah, S. R.; Yao, L.; more...
    Nature Genetics (2025)

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  • Inactivation mutations of KMT2C/D license a molecular "field effect" and prime the urothelium for tumorigenesis
    Meeting Abstract

    Wang, N.; Pachai, M. R.; Li, D.; Lee, C.; Warda, S.; Xie, G.; Qian, C.; Wong, W. P. E.; Yan, J.; Hu, W.; more...
    Cancer Research (2022)

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  • HER2 + breast cancers evade anti-HER2 therapy via a switch in driver pathway
    Journal Article

    Smith, A. E.; Ferraro, E.; Safonov, A.; Morales, C. B.; Lahuerta, E. J. A.; Li, Q.; Kulick, A.; Ross, D.; Solit, D. B.; de Stanchina, E.; more...
    Nature Communications (2021)

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  • Resistance to anti-HER2 therapy in HER2+ breast cancer is mediated by genomic alterations that switch pathway dependence from PI3K/AKT to RAS/MAPK
    Meeting Abstract

    Smith, A. E.; Chandarlapaty, S.
    Cancer Research (2020)

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  • Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas
    Journal Article

    Geyer, F. C.; Li, A.; Papanastasiou, A. D.; Smith, A.; Selenica, P.; Burke, K. A.; Edelweiss, M.; Wen, H. C.; Piscuoglio, S.; Schultheis, A. M.; more...
    Nature Communications (2018)

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  • Estrogen receptor-negative breast adenomyoepitheliomas are driven by co-occurring HRAS hotspot and PI3K pathway gene mutations: A genetic and functional analysis
    Meeting Abstract

    Geyer, F. C.; Li, A.; Papanastasiou, A. D.; Smith, A.; Selenica, P.; Burke, K. A.; Edelweiss, M.; Wen, H. C.; Piscuoglio, S.; Schultheis, A. M.; more...
    Cancer Research (2018)

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