Synapse - Renier Brentjens

Results (286)

A novel high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory acute myeloid leukemia (AML): Proof of concept and clinical implementation of precision medicine

Meeting Abstract

Shum, D.; Santos, R.; Heaney, M.; Brentjens, R.; Maslak, P.; Rosenblat, T.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
Clinical Cancer Research (2015)

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Use of a high-throughput screen of primary leukemia cells to personalize therapy for relapsed/refractory AML: Proof of concept and clinical implementation of precision medicine

Meeting Abstract

Shum, D.; Heaney, M.; Brentjens, R.; Maslak, P.; Jurcic, J.; Djaballah, H.; Frattini, M. G.
Clinical Cancer Research (2015)

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Adoptive T cell therapy with CAR modified T cells: We have a Model A Ford, can we build a Ferrari?

Meeting Abstract

Brentjens, R.
Clinical Cancer Research (2015)

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Phase I clinical trial of autologous CD19-targeted 19-28z CAR T cells in adult patients with Relapsed or refractory B-ALL

Meeting Abstract

Park, J. H.; Riviere, I.; Wang, X. Y.; Bernal, Y.; Halton, E.; Quintanilla, H.; Curran, K.; Sauter, C.; Sadelain, M.; Brentjens, R. J.
Molecular Therapy (2015)

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CD19-targeted CAR T cells "armored" to secrete IL-12 demonstrate superior efficacy against B cell acute lymphoblastic leukemia and resist treg immunosuppression

Meeting Abstract

Chang, P. S.; Lee, J. C.; Koneru, M.; Brentjens, R. J.
Molecular Therapy (2015)

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Activation signals from CD19-CAR permit NFAT-controlled inducible expression of transgenes in PBMCs

Meeting Abstract

Uchibori, R.; Teruya, T.; Ninomiya, S.; Ido, H.; Tsukahara, T.; Ohmine, K.; Urabe, M.; Saga, Y.; Kume, A.; Mizukami, H.; more...
Molecular Therapy (2015)

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Phase I trial of 19-28z chimeric antigen receptor modified T cells (19-28z CAR-T) post-high dose therapy and autologous stem cell transplant (HDT-ASCT) for relapsed and refractory (rel/ref) aggressive B-cell non-Hodgkin lymphoma (B-NHL)

Meeting Abstract

Sauter, C. S.; Riviere, I.; Bernal, Y.; Wang, X. Y.; Purdon, T.; Yoo, S.; Moskowitz, C. H.; Giralt, S.; Matasar, M. J.; Curran, K. J.; more...
Journal of Clinical Oncology (2015)

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Efficacy and safety of CD19-targeted 19-28z CAR modified T cells in adult patients with relapsed or refractory B-ALL

Meeting Abstract

Park, J. H.; Riviere, I.; Wang, X. Y.; Bernal, Y.; Purdon, T.; Halton, E.; Curran, K. J.; Sauter, C. S.; Sadelain, M.; Brentjens, R. J.
Journal of Clinical Oncology (2015)

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Chimeric antigen receptor T cells for cancer immunotherapy

Journal Article

Curran, K. J.; Brentjens, R. J.
Journal of Clinical Oncology (2015)

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CAR therapy for hematological cancers: Can success seen in the treatment of B-cell acute lymphoblastic leukemia be applied to other hematological malignancies?

Journal Article

Pegram, H. J.; Smith, E. L.; Rafiq, S.; Brentjens, R. J.
Immunotherapy (2015)

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Renier J Brentjens

Results (286)

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Journal Article

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